Arsenate reductase: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='1j9b' size='350' side='right' caption='Structure of arsenate reductase complex with arsenate, thiarsahydroxy-cysteine, sulfate and Cs+ ion (dark purple) (PDB entry [[1j9b]])' scene=''> | <StructureSection load='1j9b' size='350' side='right' caption='Structure of arsenate reductase complex with arsenate, thiarsahydroxy-cysteine, sulfate and Cs+ ion (dark purple) (PDB entry [[1j9b]])' scene=''> | ||
== Function == | |||
'''Arsenate reductase''' (AsR) catalyzes the conversion of arsenate (As) and glutaredoxin to arsenite and glutaredoxin disulfide. AsR is part of the arsenic detoxification pathway. | '''Arsenate reductase''' (AsR) catalyzes the conversion of arsenate (As V) and glutaredoxin to arsenite (As III) and glutaredoxin disulfide. | ||
== Relevance == | |||
AsR is part of the arsenic detoxification pathway. | |||
== Structural highlights == | |||
The AsR active site contains a catalytic Sys residue which forms a covalent thiolate-As V intermediate. | |||
</StructureSection> | </StructureSection> | ||