Alpha-lytic protease: Difference between revisions
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<StructureSection load=' | <StructureSection load='3pro' size='350' side='right' caption='Structure of alpha-lytic protease complex with peptidyl-boronic acid inhibitor and sulfate (PDB entry [[3pro]])' scene=''> | ||
'''Alpha-lytic protease''' (ALP) is a bacterial serine protease of the chymotrypsin family. ALP is a two-domain enzyme. One domain is a large pro region that catalyzes the folding of the protease. The second domain is the protease domain. | '''Alpha-lytic protease''' (ALP) is a bacterial serine protease of the chymotrypsin family. ALP is a two-domain enzyme. One domain is a large pro region (residues 1-199) that catalyzes the folding of the protease. The second domain is the protease domain (residues 200-397). | ||
</StructureSection> | </StructureSection> | ||
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**[[2alp]], [[1p09]], [[1tal]], [[2ull]], [[1boq]], [[1ssz]], [[2h5c]], [[1ssx]] – LeALP – ''Lysobacter enzymogenes'' <BR /> | **[[2alp]], [[1p09]], [[1tal]], [[2ull]], [[1boq]], [[1ssz]], [[2h5c]], [[1ssx]] – LeALP – ''Lysobacter enzymogenes'' <BR /> | ||
**[[1gba]], [[1gbe]], [[1gbj]], [[3urc]], [[3urd]], [[3ure]] – LeALP (mutant) <BR /> | **[[1gba]], [[1gbe]], [[1gbj]], [[3urc]], [[3urd]], [[3ure]], [[1qq4]] – LeALP (mutant) <BR /> | ||
**[[1p01]], [[1p02]], [[1p03]], [[1p04]], [[1p05]], [[1p06]], [[1p10]], [[2lpr]], [[3lpr]], [[5lpr]], [[6lpr]], [[7lpr]], [[8lpr]], [[9lpr]], [[2h5d]] – LeALP + boronic acid inhibitor <BR /> | **[[1p01]], [[1p02]], [[1p03]], [[1p04]], [[1p05]], [[1p06]], [[1p10]], [[2lpr]], [[3lpr]], [[5lpr]], [[6lpr]], [[7lpr]], [[8lpr]], [[9lpr]], [[2h5d]] – LeALP + boronic acid inhibitor <BR /> | ||
**[[1gbb]], [[1gbc]], [[1gbd]], [[1gbf]], [[1gbh]], [[1gbi]], [[1gbk]], [[1gbl]], [[1gbm]] – LeALP (mutant) + boronic acid inhibitor <BR /> | **[[1gbb]], [[1gbc]], [[1gbd]], [[1gbf]], [[1gbh]], [[1gbi]], [[1gbk]], [[1gbl]], [[1gbm]] – LeALP (mutant) + boronic acid inhibitor <BR /> | ||
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**[[3qgj]] – LeALP + peptide <BR /> | **[[3qgj]] – LeALP + peptide <BR /> | ||
*ALP | *ALP pro region | ||
**[[2pro]], [[1qrx]] – LeALP pro region <BR /> | **[[2pro]], [[1qrx]] – LeALP pro region <BR /> | ||
** | **[[1qrw]], [[3m7t]], [[3m7u]] – LeALP pro region (mutant) <BR /> | ||
**[[3pro]] | |||
*ALP pro+protease domains | |||
**[[3pro]], [[4pro]] – LeALP (mutant) <BR /> | |||
}} | }} | ||
[[Category: Topic Page]] | [[Category: Topic Page]] | ||