5'-deoxy-5'-methylthioadenosine phosphorylase: Difference between revisions

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== Function ==
== Function ==


'''5’-deoxy-5’-methylthioadenosine phosphorylase''' (MTAP)  catalyzes the reversible phosphorolysis of 5’-deoxy-5’-methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1-phosphate.  MTAP is part of the polyamine metabolism.  This reaction is the principle source of adenine in human cells.  MTAP catalyzes the first step in the methionine salvage pathway.
'''5’-deoxy-5’-methylthioadenosine phosphorylase''' (MTAP)  catalyzes the reversible phosphorolysis of <scene name='59/595220/Cv/2'>5’-deoxy-5’-methylthioadenosine (MTA)</scene> to adenine and 5-methylthio-D-ribose-1-phosphate.  MTAP is part of the polyamine metabolism.  This reaction is the principle source of adenine in human cells.  MTAP catalyzes the first step in the methionine salvage pathway.


== Disease ==
== Disease ==

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