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''' | ==Fragment bound to H.influenza NAD dependent DNA ligase== | ||
<StructureSection load='4uct' size='340' side='right' caption='[[4uct]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4uct]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UCT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UCT FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5U1:2-AMINO-6-METHYL-5-(PROPAN-2-YLOXY)-3H-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-8-IUM'>5U1</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uco|4uco]], [[4ucr|4ucr]], [[4ucs|4ucs]], [[4ucu|4ucu]], [[4ucv|4ucv]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(NAD(+)) DNA ligase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.2 6.5.1.2] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uct FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uct OCA], [http://pdbe.org/4uct PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uct RCSB], [http://www.ebi.ac.uk/pdbsum/4uct PDBsum]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/DNLJ_HAEIN DNLJ_HAEIN]] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Boriack-Sjodin, P A]] | |||
[[Category: Brassington, C]] | |||
[[Category: Carcanague, D]] | |||
[[Category: Embrey, K]] | [[Category: Embrey, K]] | ||
[[Category: | [[Category: Eyermann, C J]] | ||
[[Category: | [[Category: Giacobbe, R A]] | ||
[[Category: | [[Category: Gingipali, L]] | ||
[[Category: Gowravaram, M]] | [[Category: Gowravaram, M]] | ||
[[Category: Hale, M]] | [[Category: Hale, M]] | ||
[[Category: | [[Category: Harang, J]] | ||
[[Category: Howard, T]] | [[Category: Howard, T]] | ||
[[Category: | [[Category: Ioannidis, G]] | ||
[[Category: Jahic, H]] | [[Category: Jahic, H]] | ||
[[Category: Kutschke, A]] | [[Category: Kutschke, A]] | ||
[[Category: | [[Category: Laganas, V A]] | ||
[[Category: | [[Category: Loch, J]] | ||
[[Category: | [[Category: Miller, M D]] | ||
[[Category: Murphy-Benenato, K E]] | |||
[[Category: Oguto, H]] | [[Category: Oguto, H]] | ||
[[Category: | [[Category: Otterbein, L]] | ||
[[Category: | [[Category: Patel, S J]] | ||
[[Category: | [[Category: Shapiro, A B]] | ||
[[Category: Ligase]] | |||
Revision as of 07:02, 16 October 2015
Fragment bound to H.influenza NAD dependent DNA ligaseFragment bound to H.influenza NAD dependent DNA ligase
Structural highlights
Function[DNLJ_HAEIN] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity). |
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