2ifu: Difference between revisions
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|PDB= 2ifu |SIZE=350|CAPTION= <scene name='initialview01'>2ifu</scene>, resolution 2.600Å | |PDB= 2ifu |SIZE=350|CAPTION= <scene name='initialview01'>2ifu</scene>, resolution 2.600Å | ||
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+306'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+A+307'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+A+308'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+B+306'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+B+307'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+B+308'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Residue+B+309'>AC7</scene>, <scene name='pdbsite=AC8:So4+Binding+Site+For+Residue+C+306'>AC8</scene>, <scene name='pdbsite=AC9:So4+Binding+Site+For+Residue+C+307'>AC9</scene> and <scene name='pdbsite=BC1:So4+Binding+Site+For+Residue+D+306'>BC1</scene> | |SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+306'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+A+307'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+A+308'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+B+306'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+B+307'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+B+308'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Residue+B+309'>AC7</scene>, <scene name='pdbsite=AC8:So4+Binding+Site+For+Residue+C+306'>AC8</scene>, <scene name='pdbsite=AC9:So4+Binding+Site+For+Residue+C+307'>AC9</scene> and <scene name='pdbsite=BC1:So4+Binding+Site+For+Residue+D+306'>BC1</scene> | ||
|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene> | |LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= zgc:110177 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Danio rerio]) | |GENE= zgc:110177 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Danio rerio]) | ||
|DOMAIN= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ifu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ifu OCA], [http://www.ebi.ac.uk/pdbsum/2ifu PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2ifu RCSB]</span> | |||
}} | }} | ||
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[[Category: Mccoy, J G.]] | [[Category: Mccoy, J G.]] | ||
[[Category: Wesenberg, G E.]] | [[Category: Wesenberg, G E.]] | ||
[[Category: center for eukaryotic structural genomic]] | [[Category: center for eukaryotic structural genomic]] | ||
[[Category: cesg]] | [[Category: cesg]] | ||
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[[Category: snare complex disassembly]] | [[Category: snare complex disassembly]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:32:02 2008'' | ||
Revision as of 07:32, 26 March 2008
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| , resolution 2.600Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | , , , , , , , , and | ||||||
| Ligands: | , | ||||||
| Gene: | zgc:110177 (Danio rerio) | ||||||
| Resources: | FirstGlance, OCA, PDBsum, JenaLib, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure of a Gamma-SNAP from Danio rerio
OverviewOverview
Soluble N-ethylmaleimide-sensitive factor attachment protein gamma (gamma-SNAP) is a member of an eukaryotic protein family involved in intracellular membrane trafficking. The X-ray structure of Brachydanio rerio gamma-SNAP was determined to 2.6 A and revealed an all-helical protein comprised of an extended twisted-sheet of helical hairpins with a helical-bundle domain on its carboxy-terminal end. Structural and conformational differences between multiple observed gamma-SNAP molecules and Sec17, a SNAP family protein from yeast, are analyzed. Conformational variation in gamma-SNAP molecules is matched with great precision by the two lowest frequency normal modes of the structure. Comparison of the lowest-frequency modes from gamma-SNAP and Sec17 indicated that the structures share preferred directions of flexibility, corresponding to bending and twisting of the twisted sheet motif. We discuss possible consequences related to the flexibility of the SNAP proteins for the mechanism of the 20S complex disassembly during the SNAP receptors recycling.
About this StructureAbout this Structure
2IFU is a Single protein structure of sequence from Danio rerio. Full crystallographic information is available from OCA.
ReferenceReference
Structure and dynamics of gamma-SNAP: insight into flexibility of proteins from the SNAP family., Bitto E, Bingman CA, Kondrashov DA, McCoy JG, Bannen RM, Wesenberg GE, Phillips GN Jr, Proteins. 2008 Jan 1;70(1):93-104. PMID:17634982
Page seeded by OCA on Wed Mar 26 06:32:02 2008
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCA- Pages with broken file links
- Danio rerio
- Single protein
- Bingman, C A.
- Bitto, E.
- CESG, Center for Eukaryotic Structural Genomics.
- Jr., G N.Phillips.
- Mccoy, J G.
- Wesenberg, G E.
- Center for eukaryotic structural genomic
- Cesg
- Endocytosis/exocytosis complex
- Gamma-snap
- Membrane fusion
- Protein structure initiative
- Psi
- Snare complex disassembly