2o90: Difference between revisions
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<StructureSection load='2o90' size='340' side='right' caption='[[2o90]], [[Resolution|resolution]] 1.07Å' scene=''> | <StructureSection load='2o90' size='340' side='right' caption='[[2o90]], [[Resolution|resolution]] 1.07Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2o90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2o90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O90 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NEU:L-NEOPTERIN'>NEU</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NEU:L-NEOPTERIN'>NEU</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2nm2|2nm2]], [[2nm3|2nm3]], [[1dhn|1dhn]], [[2dhn|2dhn]], [[2oak|2oak]], [[2o9m|2o9m]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2nm2|2nm2]], [[2nm3|2nm3]], [[1dhn|1dhn]], [[2dhn|2dhn]], [[2oak|2oak]], [[2o9m|2o9m]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroneopterin_aldolase Dihydroneopterin aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.25 4.1.2.25] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroneopterin_aldolase Dihydroneopterin aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.25 4.1.2.25] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o90 RCSB], [http://www.ebi.ac.uk/pdbsum/2o90 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o90 OCA], [http://pdbe.org/2o90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o90 RCSB], [http://www.ebi.ac.uk/pdbsum/2o90 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bacillus coli migula 1895]] | |||
[[Category: Dihydroneopterin aldolase]] | [[Category: Dihydroneopterin aldolase]] | ||
[[Category: Blaszczyk, J]] | [[Category: Blaszczyk, J]] | ||
[[Category: Ji, X]] | [[Category: Ji, X]] | ||
Revision as of 19:39, 11 September 2015
Atomic resolution crystal structure of E.coli dihydroneopterin aldolase in complex with neopterinAtomic resolution crystal structure of E.coli dihydroneopterin aldolase in complex with neopterin
Structural highlights
Function[FOLB_ECOLI] Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. Can use L-threo-dihydroneopterin and D-erythro-dihydroneopterin as substrates for the formation of 6-hydroxymethyldihydropterin, but it can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin at appreciable velocity. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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