1v4p: Difference between revisions

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<StructureSection load='1v4p' size='340' side='right' caption='[[1v4p]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='1v4p' size='340' side='right' caption='[[1v4p]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1v4p]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V4P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V4P FirstGlance]. <br>
<table><tr><td colspan='2'>[[1v4p]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/'pyrococcus_shinkaii' 'pyrococcus shinkaii']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V4P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V4P FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine--tRNA_ligase Alanine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.7 6.1.1.7] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine--tRNA_ligase Alanine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.7 6.1.1.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v4p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v4p RCSB], [http://www.ebi.ac.uk/pdbsum/1v4p PDBsum], [http://www.topsan.org/Proteins/RSGI/1v4p TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v4p OCA], [http://pdbe.org/1v4p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v4p RCSB], [http://www.ebi.ac.uk/pdbsum/1v4p PDBsum], [http://www.topsan.org/Proteins/RSGI/1v4p TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/ALAXS_PYRHO ALAXS_PYRHO]] Functions in trans to edit the amino acid moiety from mischarged charged Ser-tRNA(Ala). Has little activity against Gly-tRNA(Ala).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pyrococcus shinkaii]]
[[Category: Alanine--tRNA ligase]]
[[Category: Alanine--tRNA ligase]]
[[Category: Pyrococcus horikoshii]]
[[Category: Ishijima, J]]
[[Category: Ishijima, J]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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[[Category: Alanyl-trna synthetase]]
[[Category: Alanyl-trna synthetase]]
[[Category: Ligase]]
[[Category: Ligase]]
[[Category: Pyrococcus horikoshii]]
[[Category: Rsgi]]
[[Category: Rsgi]]

Revision as of 17:40, 11 September 2015

Crystal structure of Alanyl-tRNA Synthetase from Pyrococcus horikoshii OT3Crystal structure of Alanyl-tRNA Synthetase from Pyrococcus horikoshii OT3

Structural highlights

1v4p is a 3 chain structure with sequence from 'pyrococcus shinkaii'. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:Alanine--tRNA ligase, with EC number 6.1.1.7
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, TOPSAN

Function

[ALAXS_PYRHO] Functions in trans to edit the amino acid moiety from mischarged charged Ser-tRNA(Ala). Has little activity against Gly-tRNA(Ala).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1v4p, resolution 1.45Å

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