2igi: Difference between revisions

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<StructureSection load='2igi' size='340' side='right' caption='[[2igi]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='2igi' size='340' side='right' caption='[[2igi]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2igi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IGI FirstGlance]. <br>
<table><tr><td colspan='2'>[[2igi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IGI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yta|1yta]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yta|1yta]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">orn ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K-12])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">orn ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2igi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2igi RCSB], [http://www.ebi.ac.uk/pdbsum/2igi PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2igi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2igi OCA], [http://pdbe.org/2igi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2igi RCSB], [http://www.ebi.ac.uk/pdbsum/2igi PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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*[[Ribonuclease|Ribonuclease]]
*[[Ribonuclease|Ribonuclease]]
*[[Temp|Temp]]
*[[Temp|Temp]]
*[[User:Jaime.Prilusky/Test/tree|User:Jaime.Prilusky/Test/tree]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Escherichia coli k-12]]
[[Category: Ecoli]]
[[Category: Malhotra, A]]
[[Category: Malhotra, A]]
[[Category: Zuo, Y]]
[[Category: Zuo, Y]]

Revision as of 14:07, 11 September 2015

Crystal Structure of E. coli OligoribonucleaseCrystal Structure of E. coli Oligoribonuclease

Structural highlights

2igi is a 2 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:orn (ECOLI)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[ORN_ECOLI] 3'-to-5' exoribonuclease specific for small oligoribonucleotides 2 to 5 nucleotides in length, as well as small (2 to 5 nucleotides) ssDNA oligomers. Probably responsible for the final step in mRNA degradation.[1] [2] [3]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Zhang X, Zhu L, Deutscher MP. Oligoribonuclease is encoded by a highly conserved gene in the 3'-5' exonuclease superfamily. J Bacteriol. 1998 May;180(10):2779-81. PMID:9573169
  2. ↑ Yu D, Deutscher MP. Oligoribonuclease is distinct from the other known exoribonucleases of Escherichia coli. J Bacteriol. 1995 Jul;177(14):4137-9. PMID:7608090
  3. ↑ Mechold U, Ogryzko V, Ngo S, Danchin A. Oligoribonuclease is a common downstream target of lithium-induced pAp accumulation in Escherichia coli and human cells. Nucleic Acids Res. 2006 May 8;34(8):2364-73. Print 2006. PMID:16682444 doi:http://dx.doi.org/10.1093/nar/gkl247

2igi, resolution 1.70Å

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