2it2: Difference between revisions

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<StructureSection load='2it2' size='340' side='right' caption='[[2it2]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='2it2' size='340' side='right' caption='[[2it2]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2it2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IT2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IT2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2it2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'pyrococcus_shinkaii' 'pyrococcus shinkaii']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IT2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IT2 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2it3|2it3]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2it3|2it3]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2it2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2it2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2it2 RCSB], [http://www.ebi.ac.uk/pdbsum/2it2 PDBsum], [http://www.topsan.org/Proteins/RSGI/2it2 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2it2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2it2 OCA], [http://pdbe.org/2it2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2it2 RCSB], [http://www.ebi.ac.uk/pdbsum/2it2 PDBsum], [http://www.topsan.org/Proteins/RSGI/2it2 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Y1069_PYRHO Y1069_PYRHO]] S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 (By similarity).  
[[http://www.uniprot.org/uniprot/TYW31_PYRHO TYW31_PYRHO]] S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.[HAMAP-Rule:MF_00266]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus shinkaii]]
[[Category: Lokanath, N K]]
[[Category: Lokanath, N K]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]

Revision as of 12:37, 11 September 2015

Structure of PH1069 protein from Pyrococcus horikoshiiStructure of PH1069 protein from Pyrococcus horikoshii

Structural highlights

2it2 is a 2 chain structure with sequence from 'pyrococcus shinkaii'. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
NonStd Res:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, TOPSAN

Function

[TYW31_PYRHO] S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.[HAMAP-Rule:MF_00266]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2it2, resolution 1.50Å

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OCA