1eje: Difference between revisions
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|PDB= 1eje |SIZE=350|CAPTION= <scene name='initialview01'>1eje</scene>, resolution 2.20Å | |PDB= 1eje |SIZE=350|CAPTION= <scene name='initialview01'>1eje</scene>, resolution 2.20Å | ||
|SITE= | |SITE= | ||
|LIGAND= <scene name='pdbligand= | |LIGAND= <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1853 COG1853]</span> | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eje OCA], [http://www.ebi.ac.uk/pdbsum/1eje PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1eje RCSB]</span> | |||
}} | }} | ||
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[[Category: NESG, Northeast Structural Genomics Consortium.]] | [[Category: NESG, Northeast Structural Genomics Consortium.]] | ||
[[Category: Saridakis, V.]] | [[Category: Saridakis, V.]] | ||
[[Category: fmn-binding protein]] | [[Category: fmn-binding protein]] | ||
[[Category: nesg]] | [[Category: nesg]] | ||
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[[Category: structural genomic]] | [[Category: structural genomic]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 05:51:47 2008'' | ||
Revision as of 06:51, 26 March 2008
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| , resolution 2.20Å | |||||||
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| Ligands: | , , | ||||||
| Domains: | COG1853 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, JenaLib, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CRYSTAL STRUCTURE OF AN FMN-BINDING PROTEIN
OverviewOverview
A set of 424 nonmembrane proteins from Methanobacterium thermoautotrophicum were cloned, expressed and purified for structural studies. Of these, approximately 20% were found to be suitable candidates for X-ray crystallographic or NMR spectroscopic analysis without further optimization of conditions, providing an estimate of the number of the most accessible structural targets in the proteome. A retrospective analysis of the experimental behavior of these proteins suggested some simple relations between sequence and solubility, implying that data bases of protein properties will be useful in optimizing high throughput strategies. Of the first 10 structures determined, several provided clues to biochemical functions that were not detectable from sequence analysis, and in many cases these putative functions could be readily confirmed by biochemical methods. This demonstrates that structural proteomics is feasible and can play a central role in functional genomics.
About this StructureAbout this Structure
1EJE is a Single protein structure of sequence from Methanothermobacter thermautotrophicus. Full crystallographic information is available from OCA.
ReferenceReference
Structural proteomics of an archaeon., Christendat D, Yee A, Dharamsi A, Kluger Y, Savchenko A, Cort JR, Booth V, Mackereth CD, Saridakis V, Ekiel I, Kozlov G, Maxwell KL, Wu N, McIntosh LP, Gehring K, Kennedy MA, Davidson AR, Pai EF, Gerstein M, Edwards AM, Arrowsmith CH, Nat Struct Biol. 2000 Oct;7(10):903-9. PMID:11017201
Page seeded by OCA on Wed Mar 26 05:51:47 2008
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCA- Pages with broken file links
- Methanothermobacter thermautotrophicus
- Single protein
- Arrowsmith, C.
- Bochkarev, A.
- Christendat, D.
- Edwards, A M.
- NESG, Northeast Structural Genomics Consortium.
- Saridakis, V.
- Fmn-binding protein
- Nesg
- Northeast structural genomics consortium
- Protein structure initiative
- Psi
- Structural genomic