2epr: Difference between revisions

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<StructureSection load='2epr' size='340' side='right' caption='[[2epr]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2epr' size='340' side='right' caption='[[2epr]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2epr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EPR FirstGlance]. <br>
<table><tr><td colspan='2'>[[2epr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EPR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PATZ1, PATZ, RIAZ, ZBTB19, ZNF278, ZSG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PATZ1, PATZ, RIAZ, ZBTB19, ZNF278, ZSG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2epr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2epr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2epr RCSB], [http://www.ebi.ac.uk/pdbsum/2epr PDBsum], [http://www.topsan.org/Proteins/RSGI/2epr TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2epr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2epr OCA], [http://pdbe.org/2epr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2epr RCSB], [http://www.ebi.ac.uk/pdbsum/2epr PDBsum], [http://www.topsan.org/Proteins/RSGI/2epr TOPSAN]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Inoue, M]]
[[Category: Inoue, M]]
[[Category: Kigawa, T]]
[[Category: Kigawa, T]]

Revision as of 09:14, 11 September 2015

Solution structure of the secound zinc finger domain of Zinc finger protein 278Solution structure of the secound zinc finger domain of Zinc finger protein 278

Structural highlights

2epr is a 1 chain structure with sequence from Human. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:PATZ1, PATZ, RIAZ, ZBTB19, ZNF278, ZSG (HUMAN)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, TOPSAN

Disease

[PATZ1_HUMAN] Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.

Function

[PATZ1_HUMAN] Transcriptional repressor.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Fedele M, Benvenuto G, Pero R, Majello B, Battista S, Lembo F, Vollono E, Day PM, Santoro M, Lania L, Bruni CB, Fusco A, Chiariotti L. A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor. J Biol Chem. 2000 Mar 17;275(11):7894-901. PMID:10713105
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