1bcg: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1bcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hottentotta_judaicus Hottentotta judaicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BCG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BCG FirstGlance]. <br> | <table><tr><td colspan='2'>[[1bcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hottentotta_judaicus Hottentotta judaicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BCG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BCG FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bcg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bcg RCSB], [http://www.ebi.ac.uk/pdbsum/1bcg PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bcg OCA], [http://pdbe.org/1bcg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bcg RCSB], [http://www.ebi.ac.uk/pdbsum/1bcg PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/ | [[http://www.uniprot.org/uniprot/SIXE_HOTJU SIXE_HOTJU]] Excitatory insect toxins induce a spastic paralysis. They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active only on insects. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 1bcg" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||