2jha: Difference between revisions
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|PDB= 2jha |SIZE=350|CAPTION= <scene name='initialview01'>2jha</scene>, resolution 3.40Å | |PDB= 2jha |SIZE=350|CAPTION= <scene name='initialview01'>2jha</scene>, resolution 3.40Å | ||
|SITE= <scene name='pdbsite=AC1:Gun+Binding+Site+For+Chain+A'>AC1</scene> | |SITE= <scene name='pdbsite=AC1:Gun+Binding+Site+For+Chain+A'>AC1</scene> | ||
|LIGAND= <scene name='pdbligand=GP3:DIGUANOSINE-5 | |LIGAND= <scene name='pdbligand=GP3:DIGUANOSINE-5'-TRIPHOSPHATE'>GP3</scene> and <scene name='pdbligand=GUN:GUANINE'>GUN</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
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[[Category: virion protein]] | [[Category: virion protein]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:26:30 2008'' | ||
Revision as of 16:26, 23 March 2008
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THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE
OverviewOverview
Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.
About this StructureAbout this Structure
2JHA is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa). Full crystallographic information is available from OCA.
ReferenceReference
Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654
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