2j0v: Difference between revisions
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|PDB= 2j0v |SIZE=350|CAPTION= <scene name='initialview01'>2j0v</scene>, resolution 1.78Å | |PDB= 2j0v |SIZE=350|CAPTION= <scene name='initialview01'>2j0v</scene>, resolution 1.78Å | ||
|SITE= <scene name='pdbsite=AC1:Mg+Binding+Site+For+Chain+D'>AC1</scene> | |SITE= <scene name='pdbsite=AC1:Mg+Binding+Site+For+Chain+D'>AC1</scene> | ||
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=GDP:GUANOSINE-5 | |LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=GDP:GUANOSINE-5'-DIPHOSPHATE'>GDP</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
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[[Category: rop9]] | [[Category: rop9]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:23:40 2008'' | ||
Revision as of 16:23, 23 March 2008
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THE CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA RAC7-ROP9: THE FIRST RAS SUPERFAMILY GTPASE FROM THE PLANT KINGDOM
OverviewOverview
Arabidopsis thaliana RAC/ROP GTPases constitute a plant specific Rho GTPase family in the RAS superfamily, which has been implicated in numerous pivotal signalling cascades in plants. Research has shown that plants in some cases have evolved different modes of regulating Rho GTPase activity as compared to the equivalent systems in animals and yeast. In order to gain structural insight into plant signaling at the molecular level, we have determined the first crystal structure of a RAC-like GTPase belonging to the RAS superfamily from the plant kingdom. The structure of AtRAC7/ROP9 bound to GDP was solved at a resolution of 1.78 A. We have found that the structure of plant Rho GTPases is based upon a conserved G-domain architecture, but structural differences were found concerning the insert region and switch II region of the protein.
About this StructureAbout this Structure
2J0V is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.
ReferenceReference
The crystal structure of Arabidopsis thaliana RAC7/ROP9: the first RAS superfamily GTPase from the plant kingdom., Sormo CG, Leiros I, Brembu T, Winge P, Os V, Bones AM, Phytochemistry. 2006 Nov;67(21):2332-40. Epub 2006 Sep 26. PMID:17005216
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