2ezg: Difference between revisions
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<StructureSection load='2ezg' size='340' side='right' caption='[[2ezg]], [[NMR_Ensembles_of_Models | 35 NMR models]]' scene=''> | <StructureSection load='2ezg' size='340' side='right' caption='[[2ezg]], [[NMR_Ensembles_of_Models | 35 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ezg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2ezg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EZG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EZG FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ezf|2ezf]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ezf|2ezf]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ezg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ezg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ezg RCSB], [http://www.ebi.ac.uk/pdbsum/2ezg PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ezg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ezg OCA], [http://pdbe.org/2ezg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ezg RCSB], [http://www.ebi.ac.uk/pdbsum/2ezg PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | |||
[[http://www.uniprot.org/uniprot/HMGA1_HUMAN HMGA1_HUMAN]] A chromosomal aberration involving HMGA1 is found in pulmonary chondroid hamartoma. Translocation t(6;14)(p21;q23-24) with RAD51B. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/HMGA1_HUMAN HMGA1_HUMAN]] HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2ezg" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[High mobility group protein|High mobility group protein]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Human]] | ||
[[Category: Bewley, C]] | [[Category: Bewley, C]] | ||
[[Category: Clore, G M]] | [[Category: Clore, G M]] | ||