1gzd: Difference between revisions

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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gzv|1gzv]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gzv|1gzv]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gzd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gzd RCSB], [http://www.ebi.ac.uk/pdbsum/1gzd PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gzd OCA], [http://pdbe.org/1gzd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gzd RCSB], [http://www.ebi.ac.uk/pdbsum/1gzd PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 14:17, 10 September 2015

Crystal structure of pig phosphophoglucose isomeraseCrystal structure of pig phosphophoglucose isomerase

Structural highlights

1gzd is a 1 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:Glucose-6-phosphate isomerase, with EC number 5.3.1.9
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[G6PI_PIG] Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1gzd, resolution 2.50Å

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