5ac0: Difference between revisions
m Protected "5ac0" [edit=sysop:move=sysop] |
No edit summary |
||
Line 1: | Line 1: | ||
''' | ==ovis aries Aldehyde Dehydrogenase 1A1 in complex with a duocarmycin analog== | ||
<StructureSection load='5ac0' size='340' side='right' caption='[[5ac0]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ac0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AC0 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K9P:1-[(1S)-1-METHYL-5-OXIDANYL-1,2-DIHYDROBENZO[E]INDOL-3-YL]HEXAN-1-ONE'>K9P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5abm|5abm]], [[5ac1|5ac1]], [[5ac2|5ac2]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Retinal_dehydrogenase Retinal dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.36 1.2.1.36] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ac0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ac0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5ac0 RCSB], [http://www.ebi.ac.uk/pdbsum/5ac0 PDBsum]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/AL1A1_SHEEP AL1A1_SHEEP]] Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Retinal dehydrogenase]] | |||
[[Category: Blank, I D]] | |||
[[Category: Harteis, S]] | |||
[[Category: Koch, M F]] | |||
[[Category: Ochsenfeld, C]] | |||
[[Category: Pestel, G]] | [[Category: Pestel, G]] | ||
[[Category: Schneider, S]] | [[Category: Schneider, S]] | ||
[[Category: | [[Category: Sieber, S A]] | ||
[[Category: | [[Category: Tietze, L F]] | ||
[[Category: | [[Category: Aldehyde dehydrogenase activity]] | ||
[[Category: | [[Category: Oxidation-reduction process]] | ||
[[Category: Oxidoreductase]] |