4zme: Difference between revisions

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'''Unreleased structure'''
==Crystal Structure of the Alpha-kinase Domain of Myosin-II Heavy Chain Kinase A in Complex with Adenosine==
 
<StructureSection load='4zme' size='340' side='right' caption='[[4zme]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
The entry 4zme is ON HOLD  until Paper Publication
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4zme]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZME OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZME FirstGlance]. <br>
Authors: Ye, Q., Jia, Z.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PHD:ASPARTYL+PHOSPHATE'>PHD</scene></td></tr>
Description: Crystal Structure of the Alpha-kinase Domain of Myosin-II Heavy Chain Kinase A in Complex with Adenosine
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lla|3lla]], [[3lmh|3lmh]], [[3lkm|3lkm]], [[3lmi|3lmi]], [[3pdt|3pdt]]</td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Myosin_heavy-chain]_kinase [Myosin heavy-chain] kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.7 2.7.11.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zme FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zme OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4zme RCSB], [http://www.ebi.ac.uk/pdbsum/4zme PDBsum]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/MHCKA_DICDI MHCKA_DICDI]] Phosphorylates threonine in the C-terminal tail region of myosin II heavy chain. This phosphorylation is critical in regulating the assembly and disassembly of myosin II filament. Requires autophosphorylation for activity.
__TOC__
</StructureSection>
[[Category: Jia, Z]]
[[Category: Jia, Z]]
[[Category: Ye, Q]]
[[Category: Ye, Q]]
[[Category: Aspartyl phosphate intermediate]]
[[Category: Transferase]]

Revision as of 15:26, 20 August 2015

Crystal Structure of the Alpha-kinase Domain of Myosin-II Heavy Chain Kinase A in Complex with AdenosineCrystal Structure of the Alpha-kinase Domain of Myosin-II Heavy Chain Kinase A in Complex with Adenosine

Structural highlights

4zme is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
NonStd Res:
Activity:[Myosin_heavy-chain_kinase [Myosin heavy-chain] kinase], with EC number 2.7.11.7
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[MHCKA_DICDI] Phosphorylates threonine in the C-terminal tail region of myosin II heavy chain. This phosphorylation is critical in regulating the assembly and disassembly of myosin II filament. Requires autophosphorylation for activity.

4zme, resolution 1.98Å

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OCA
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