Porin: Difference between revisions
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[[Porin]] or '''Outer Membrane Proteins''' '''(Omps)''' act as channels which allow passive diffusion of sugars, ions and amino acids. They are beta barrel proteins which traverse the cell membrane. In ''E. coli'' they are named according to their genes: C, F, G (OmpC, OmpF, OmpG). Voltage-Dependent Anion Channel (VDAC) are ion channel Omps found in outer mitochondrial membrane. In Pseudomonas aeruginosa the porin gene products are named OprD, OprE, OprK, OprP. '''Maltoporin''' (LamB) facilitates the diffusion of maltodextrin across the membrane. See more details in<br /> | [[Porin]] or '''Outer Membrane Proteins''' '''(Omps)''' act as channels which allow passive diffusion of sugars, ions and amino acids. They are beta barrel proteins which traverse the cell membrane. In ''E. coli'' they are named according to their genes: C, F, G, etc. (OmpC, OmpF, OmpG). Voltage-Dependent Anion Channel (VDAC) are ion channel Omps found in outer mitochondrial membrane. In ''Pseudomonas aeruginosa'' the porin gene products are named OprD, OprE, OprK, OprP, etc. and OpdC, OpdH, etc. '''Maltoporin''' (LamB) facilitates the diffusion of maltodextrin across the membrane. See more details in<br /> | ||
*[[Osmoporin OmpC (E. coli)]]<br /> | *[[Osmoporin OmpC (E. coli)]]<br /> | ||
*[[OmpF]]<br /> | *[[OmpF]]<br /> | ||
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
* | *OmpA | ||
**[[ | **[[3nb3]] – EcOmpA + EcOmpC – ''Escherichia coli'' – EM<br /> | ||
**[[ | **[[1bxw]], [[1qjp]] – EcOmpA transmembrane domain (mutant)<br /> | ||
**[[ | **[[2jmm]] – EcOmpA transmembrane domain - NMR<br /> | ||
**[[ | **[[1g90]], [[2ge4]] – EcOmpA transmembrane domain (mutant) - NMR<br /> | ||
**[[2kgw]] – MtOmpA C terminal – ''Mycobacterium tuberculosis'' – NMR<br /> | **[[2kgw]] – MtOmpA C terminal – ''Mycobacterium tuberculosis'' – NMR<br /> | ||
**[[2ksm]] – MtOmpA BON domain – NMR<br /> | **[[2ksm]] – MtOmpA BON domain – NMR<br /> | ||
**[[ | **[[2k0l]] – KpOmpA transmembrane domain – ''Klebsiella pneumoniae'' - NMR<br /> | ||
**[[ | **[[4erh]] – SeOmpA residues 205-349 – ''Salmonella enterica''<br /> | ||
*OmpB | |||
* | |||
**[[3a2r]] – NmOmpB – ''Neisseria meningitides''<br /> | **[[3a2r]] – NmOmpB – ''Neisseria meningitides''<br /> | ||
**[[ | **[[3a2s]], [[3a2t]] – NmOmpB+sugars<br /> | ||
**[[3a2u]] - NmOmpB+AMPPNP<br /> | |||
**[[4gey]], [[4gf4]] – OmpB – ''Pseudomonas putida''<br /> | |||
*OmpC | |||
**[[2xe5]], [[2xe1]], [[2xe2]], [[2xe3]], [[2j1n]], [[2xg6]] – EcOmpC <br /> | |||
**[[2zle]] - EcOmpC + protease DO – EM<br /> | |||
**[[4a8d]] - EcOmpC + DEGP – EM<br /> | |||
**[[2j4u]] – EcOmpC+lactotransferrin fragment<br /> | |||
**[[3upg]], [[3uu2]] – SeOmpC <br /> | |||
*OmpF | |||
**[[3k19]], [[3k1b]], [[2zfg]], [[1omf]], [[2omf]], [[1opf]], [[3poq]], [[3pou]], [[3pox]], [[4jfb]], [[4lse]], [[4lsf]], [[4lsh]], [[4lsi]] – EcOmpF<br /> | |||
**[[1hxt]], [[1hxu]], [[1hxx]], [[1bt9]], [[1gfm]], [[1gfn]], [[1gfo]], [[1gfp]], [[1gfq]], [[1mpf]] – EcOmpF (mutant) <br /> | |||
**[[2zld]] – EcOmpF+colicin E3<br /> | |||
**[[3o0e]] - EcOmpF+colicin peptide<br /> | |||
**[[3hw9]], [[3hwb]] – EcOmpF+ions<br /> | |||
**[[3fyx]] – EcOmpF+dibenzo-18-crown-6<br /> | |||
**[[4gcp]], [[4gcq]], [[4gcs]] – EcOmpF + antibiotic<br /> | |||
**[[3nsg]] – StOmpF - ''Salmonella typhimurium''<br /> | |||
**[[4kr4]], [[4kr8]], [[4kra]] – StOmpF + antibiotics<br /> | |||
*OmpG | |||
**[[2iwv]], [[2iww]], [[2f1c]], [[4ctd]] – EcOmpG<br /> | |||
**[[2x9k]], [[2wvp]] - EcOmpG (mutant) <br /> | |||
**[[2jqy]] – EcOmpG - NMR<br /> | |||
*OmpK | |||
**[[1osm]] – KpOmpK36 <br /> | |||
*OmpR | |||
**[[1opc]] - EcOmpR C terminal<br /> | |||
*Omp32 | |||
**[[2fgr]] - DaOmp32 – ''Delftia acidovorans''<br /> | |||
**[[1e54]] – Omp32+sulfate – ''Comamonas acidovorans''<br /> | |||
**[[2fgq]] – DaOmp32+malate<br /> | |||
*OprB | |||
**[[4gf4]], [[4gey]] – PaOprB – ''Pseudomonas aeruginosa''<br /> | |||
*OprD | |||
**[[2odj]], [[3sy7]], [[4foz]] – PaOprD<br /> | **[[2odj]], [[3sy7]], [[4foz]] – PaOprD<br /> | ||
*OprE | |||
**[[4frx]] – PaOprE<br /> | **[[4frx]] – PaOprE<br /> | ||
**[[3szd]] | |||
*OprF | |||
**[[3szd]] – PaOprF<br /> | |||
**[[4rlc]] – PaOprF N terminal<br /> | **[[4rlc]] – PaOprF N terminal<br /> | ||
**[[ | |||
*OprG | |||
**[[2x27]] - PaOprG<br /> | |||
*OprH | |||
**[[2lhf]] – PaOprH - NMR<br /> | |||
*OprK | |||
**[[2qtk]], [[2y2x]], [[3sys]] – PaOprK<br /> | **[[2qtk]], [[2y2x]], [[3sys]] – PaOprK<br /> | ||
*OprL | |||
**[[3t0s]] - PaOprL<br /> | **[[3t0s]] - PaOprL<br /> | ||
**[[2y0k]], [[2y0l]], [[3szv]] – | |||
**[[3syb]] – | *OprM | ||
**[[ | |||
**[[3d5k]], [[1wp1]], [[4y1k]] - PaOprM<br /> | |||
*OprP | |||
**[[2o4v]] – PaOprP+phosphate<br /> | |||
*OprQ | |||
**[[3t24]] – PaOprQ<br /> | |||
*OpdC (histidine porin) | |||
**[[3sy9]] – PaOprC <br /> | |||
*OpdH (cis-aconitate porin) | |||
**[[3t20]] – PaOprH<br /> | |||
*OpdO (pyroglutatmate porin) | |||
**[[2y0k]], [[2y0l]], [[3szv]] – PaOpdO<br /> | |||
*OpdP (glycine-glutamate dipeptide porin) | |||
**[[3syb]] – PaOpdP<br /> | |||
*Omp | |||
**[[1pho]] - EcOmp<br /> | |||
**[[3jty]] – Omp – ''Pseudomonas fluorescens''<br /> | **[[3jty]] – Omp – ''Pseudomonas fluorescens''<br /> | ||
**[[2v9u]] – MsOmp rim domain – ''Mycobacteria smegmatis''<br /> | **[[2v9u]] – MsOmp rim domain – ''Mycobacteria smegmatis''<br /> | ||
**[[1uun]] – MsOmp (mutant) | **[[1uun]] – MsOmp (mutant) <br /> | ||
**[[2prn]], [[1bh3]], [[3prn]], [[5prn]], [[6prn]], [[7prn]], [[8prn]] – RbOmp (mutant) - ''Rhodopseudomonas blastica''<br /> | **[[2prn]], [[1bh3]], [[3prn]], [[5prn]], [[6prn]], [[7prn]], [[8prn]] – RbOmp (mutant) - ''Rhodopseudomonas blastica''<br /> | ||
**[[1prn]] | **[[1prn]] – RbOmp<br /> | ||
**[[ | **[[1h6s]] – RbOmp+inserted sequence<br /> | ||
**[[2por]], [[3por]] – Omp – ''Rhodobacter capsulatus''<br /> | **[[2por]], [[3por]] – Omp – ''Rhodobacter capsulatus''<br /> | ||
**[[4aui]] – Omp – ''Neisseria gonorrheae''<br /> | **[[4aui]] – Omp – ''Neisseria gonorrheae''<br /> | ||
**[[4fqe]] – DdOmp KDGM – ''Dickeya dadantii''<br /> | **[[4fqe]] – DdOmp KDGM – ''Dickeya dadantii''<br /> | ||
**[[4pr7]] – DdOmp KDGM + oligogalactouronate<br /> | |||
* | *Sugar-specific porin | ||
**[[ | **[[1a0s]] – StOmp<br /> | ||
**[[1oh2]], [[1a0t]] – StOmp+sucrose<br /> | |||
**[[1oh2]], [[1a0t]] | |||
*Maltoporin | *Maltoporin | ||
**[[1mal]] – EcLamB<br /> | **[[1mal]] – EcLamB<br /> | ||
**[[2mpr]] – StLamB<br /> | **[[1af6]], [[1mpq]], [[1mpm]], [[1mpn]], [[1mpo]] – EcLamB+sugars<br /> | ||
**[[2mpr]], [[1mpr]] – StLamB<br /> | |||
Voltage-Dependent Anion Channel | |||
See [[Ion channels]] | |||
}} | }} | ||
==References== | ==References== |