5c7e: Difference between revisions

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'''Unreleased structure'''
==Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis IAA10 peptide==
 
<StructureSection load='5c7e' size='340' side='right' caption='[[5c7e]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
The entry 5c7e is ON HOLD  until Paper Publication
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5c7e]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C7E FirstGlance]. <br>
Authors: Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zhe|4zhe]], [[5c6q|5c6q]], [[5c6v|5c6v]], [[5c7f|5c7f]]</td></tr>
Description: Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis IAA10 peptide
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c7e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5c7e RCSB], [http://www.ebi.ac.uk/pdbsum/5c7e PDBsum]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
[[Category: Xu, H.E]]
== Function ==
[[http://www.uniprot.org/uniprot/IAA10_ARATH IAA10_ARATH]] Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.<ref>PMID:12036262</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Brunzelle, J S]]
[[Category: Gu, X]]
[[Category: Ke, J]]
[[Category: Ma, H]]
[[Category: Ma, H]]
[[Category: Melcher, K]]
[[Category: Melcher, K]]
[[Category: Gu, X]]
[[Category: Xu, H E]]
[[Category: Brunzelle, J.S]]
[[Category: Alpha-helical structure]]
[[Category: Ke, J]]
[[Category: Plant development]]
[[Category: Plant transcriptional repression]]
[[Category: Tetrameric protein]]
[[Category: Transcription]]
[[Category: Transcriptional corepressor]]

Revision as of 23:21, 5 August 2015

Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis IAA10 peptideCrystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis IAA10 peptide

Structural highlights

5c7e is a 12 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[IAA10_ARATH] Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.[1]

References

  1. Liscum E, Reed JW. Genetics of Aux/IAA and ARF action in plant growth and development. Plant Mol Biol. 2002 Jun-Jul;49(3-4):387-400. PMID:12036262

5c7e, resolution 3.10Å

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