4u3f: Difference between revisions

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'''Unreleased structure'''
==Cytochrome bc1 complex from chicken with designed inhibitor bound==
 
<StructureSection load='4u3f' size='340' side='right' caption='[[4u3f]], [[Resolution|resolution]] 3.23&Aring;' scene=''>
The entry 4u3f is ON HOLD  until Paper Publication
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4u3f]] is a 20 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U3F FirstGlance]. <br>
Authors: Huang, L.-S., Zhu, X.-L., Yang, G.F., Berry, E.A.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=CDL:CARDIOLIPIN'>CDL</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEE:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>PEE</scene>, <scene name='pdbligand=U10:UBIQUINONE-10'>U10</scene>, <scene name='pdbligand=Y52:METHYL+(2E)-3-METHOXY-2-(2-{[(5-METHOXY-1,3-BENZOTHIAZOL-2-YL)SULFANYL]METHYL}PHENYL)PROP-2-ENOATE'>Y52</scene></td></tr>
 
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AME:N-ACETYLMETHIONINE'>AME</scene>, <scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene>, <scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
Description: Cytochrome bc1 complex from chicken with designed inhibitor bound
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tgu|3tgu]]</td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquinol--cytochrome-c_reductase Ubiquinol--cytochrome-c reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.2.2 1.10.2.2] </span></td></tr>
[[Category: Zhu, X.-L]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u3f RCSB], [http://www.ebi.ac.uk/pdbsum/4u3f PDBsum]</span></td></tr>
[[Category: Yang, G.F]]
</table>
[[Category: Huang, L.-S]]
== Function ==
[[Category: Berry, E.A]]
[[http://www.uniprot.org/uniprot/D0VX30_CHICK D0VX30_CHICK]] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain (By similarity).[PIRNR:PIRNR000022] [[http://www.uniprot.org/uniprot/CYB_CHICK CYB_CHICK]] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity). [[http://www.uniprot.org/uniprot/UCRI_CHICK UCRI_CHICK]] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity). [[http://www.uniprot.org/uniprot/D0VX28_CHICK D0VX28_CHICK]] This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.[PIRNR:PIRNR000019]
__TOC__
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Ubiquinol--cytochrome-c reductase]]
[[Category: Berry, E A]]
[[Category: Huang, L S]]
[[Category: Yang, G F]]
[[Category: Zhu, X L]]
[[Category: 2fe-2]]
[[Category: Azoxystrobin]]
[[Category: Complex iii]]
[[Category: Cytochrome b]]
[[Category: Cytochrome bc1]]
[[Category: Cytochrome c1]]
[[Category: Electron transport]]
[[Category: Heme]]
[[Category: Heme protein]]
[[Category: Inner membrane]]
[[Category: Iron]]
[[Category: Iron-sulfur]]
[[Category: Membrane binding]]
[[Category: Membrane protein]]
[[Category: Metal-binding]]
[[Category: Mitochondrial inner membrane]]
[[Category: Mitochondrion]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Redox enzyme respiratory chain]]
[[Category: Respiratory chain]]
[[Category: Rieske iron sulfur protein]]
[[Category: Stigmatellin]]
[[Category: Strobilurin]]
[[Category: Transmembrane]]
[[Category: Ubiquinone]]

Revision as of 17:48, 29 July 2015

Cytochrome bc1 complex from chicken with designed inhibitor boundCytochrome bc1 complex from chicken with designed inhibitor bound

Structural highlights

4u3f is a 20 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , , , , , , ,
NonStd Res:, ,
Activity:Ubiquinol--cytochrome-c reductase, with EC number 1.10.2.2
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[D0VX30_CHICK] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain (By similarity).[PIRNR:PIRNR000022] [CYB_CHICK] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity). [UCRI_CHICK] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity). [D0VX28_CHICK] This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.[PIRNR:PIRNR000019]

4u3f, resolution 3.23Å

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