5ak7: Difference between revisions
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''' | ==Structure of wt Porphyromonas gingivalis peptidylarginine deiminase== | ||
<StructureSection load='5ak7' size='340' side='right' caption='[[5ak7]], [[Resolution|resolution]] 1.46Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ak7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AK7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AK7 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ak8|5ak8]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ak7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ak7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5ak7 RCSB], [http://www.ebi.ac.uk/pdbsum/5ak7 PDBsum]</span></td></tr> | |||
[[ | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/PAD_PORGI PAD_PORGI]] Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth.<ref>PMID:10377098</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Burgess-Brown, N]] | [[Category: Burgess-Brown, N]] | ||
[[Category: Kiyani, W]] | [[Category: Kiyani, W]] | ||
[[Category: Kopec, J]] | [[Category: Kopec, J]] | ||
[[Category: Montgomery, A]] | [[Category: Montgomery, A]] | ||
[[Category: Nowak, R]] | |||
[[Category: Shrestha, L]] | |||
[[Category: Venables, P J]] | |||
[[Category: Yue, W W]] | |||
[[Category: Hydrolase]] | |||
Revision as of 17:20, 22 July 2015
Structure of wt Porphyromonas gingivalis peptidylarginine deiminaseStructure of wt Porphyromonas gingivalis peptidylarginine deiminase
Structural highlights
Function[PAD_PORGI] Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth.[1] References |
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