4thn: Difference between revisions

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[[Image:4thn.jpg|left|200px]]<br /><applet load="4thn" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:4thn.jpg|left|200px]]
caption="4thn, resolution 2.5&Aring;" />
 
'''THE CRYSTAL STRUCTURE OF ALPHA-THROMBIN-HIRUNORM IV COMPLEX REVEALS A NOVEL SPECIFICITY SITE RECOGNITION MODE.'''<br />
{{Structure
|PDB= 4thn |SIZE=350|CAPTION= <scene name='initialview01'>4thn</scene>, resolution 2.5&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE=
}}
 
'''THE CRYSTAL STRUCTURE OF ALPHA-THROMBIN-HIRUNORM IV COMPLEX REVEALS A NOVEL SPECIFICITY SITE RECOGNITION MODE.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
4THN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4THN OCA].  
4THN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4THN OCA].  


==Reference==
==Reference==
The crystal structure of alpha-thrombin-hirunorm IV complex reveals a novel specificity site recognition mode., Lombardi A, De Simone G, Nastri F, Galdiero S, Della Morte R, Staiano N, Pedone C, Bolognesi M, Pavone V, Protein Sci. 1999 Jan;8(1):91-5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10210187 10210187]
The crystal structure of alpha-thrombin-hirunorm IV complex reveals a novel specificity site recognition mode., Lombardi A, De Simone G, Nastri F, Galdiero S, Della Morte R, Staiano N, Pedone C, Bolognesi M, Pavone V, Protein Sci. 1999 Jan;8(1):91-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10210187 10210187]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Staiano, N.]]
[[Category: Staiano, N.]]
[[Category: NAG]]
[[Category: NAG]]
[[Category: antithrombotics]]
[[Category: antithrombotic]]
[[Category: complex (serine protease/inhibitor)]]
[[Category: complex (serine protease/inhibitor)]]
[[Category: hirudin-like binding mode]]
[[Category: hirudin-like binding mode]]
[[Category: hirunorms]]
[[Category: hirunorm]]
[[Category: thrombin]]
[[Category: thrombin]]
[[Category: thrombin synthetic inhibitors]]
[[Category: thrombin synthetic inhibitor]]


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