486d: Difference between revisions

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File:486d.gif

, resolution 7.5Å

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X-RAY CRYSTAL STRUCTURES OF 70S RIBOSOME FUNCTIONAL COMPLEXES

OverviewOverview

Structures of 70S ribosome complexes containing messenger RNA and transfer RNA (tRNA), or tRNA analogs, have been solved by x-ray crystallography at up to 7.8 angstrom resolution. Many details of the interactions between tRNA and the ribosome, and of the packing arrangements of ribosomal RNA (rRNA) helices in and between the ribosomal subunits, can be seen. Numerous contacts are made between the 30S subunit and the P-tRNA anticodon stem-loop; in contrast, the anticodon region of A-tRNA is much more exposed. A complex network of molecular interactions suggestive of a functional relay is centered around the long penultimate stem of 16S rRNA at the subunit interface, including interactions involving the "switch" helix and decoding site of 16S rRNA, and RNA bridges from the 50S subunit.

About this StructureAbout this Structure

486D is a Protein complex structure of sequences from Escherichia coli, Saccharomyces cerevisiae and Thermus thermophilus. Full crystallographic information is available from OCA.

ReferenceReference

X-ray crystal structures of 70S ribosome functional complexes., Cate JH, Yusupov MM, Yusupova GZ, Earnest TN, Noller HF, Science. 1999 Sep 24;285(5436):2095-104. PMID:10497122

Page seeded by OCA on Thu Mar 20 19:08:46 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:486d.gif|left|200px]]<br /><applet load="486d" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:486d.gif|left|200px]]
-caption="486d, resolution 7.5&Aring;" />
-'''X-RAY CRYSTAL STRUCTURES OF 70S RIBOSOME FUNCTIONAL COMPLEXES'''<br />
+ {{Structure
+|PDB= 486d |SIZE=350|CAPTION= <scene name='initialview01'>486d</scene>, resolution 7.5&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=IR:IRIDIUM ION'>IR</scene>
+|ACTIVITY=
+|GENE=
+}}
+'''X-RAY CRYSTAL STRUCTURES OF 70S RIBOSOME FUNCTIONAL COMPLEXES'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=IR:'>IR</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=486D OCA].
+D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=486D OCA].
 ==Reference==
-X-ray crystal structures of 70S ribosome functional complexes., Cate JH, Yusupov MM, Yusupova GZ, Earnest TN, Noller HF, Science. 1999 Sep 24;285(5436):2095-104. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10497122 10497122]
+X-ray crystal structures of 70S ribosome functional complexes., Cate JH, Yusupov MM, Yusupova GZ, Earnest TN, Noller HF, Science. 1999 Sep 24;285(5436):2095-104. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10497122 10497122]
 [[Category: Escherichia coli]]
 [[Category: Protein complex]]
@@ Line 24: / Line 33: @@
 [[Category: trna]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:12:37 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:08:46 2008''