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Michal Harel (talk | contribs) New page: <StructureSection load='4d10' size='340' side='right' caption='Caption for this structure' scene=''> '''COP9 (COnstitutive Photomorphogenesis 9) signalosome''' catalyzes the hydrolysis of... |
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<StructureSection load='4d10' size='340' side='right' caption='Human COP9 signalosome subunits 1 (grey and wheat), 2 (green and blue), 3 (pink and rust), 4 (yellow and aqua), 5 (magenta and olive), 6 (cyan and ), 7A (gold and ), 8 (red and neon green) (PDB code [[4d10]])' scene=''> | |||
<StructureSection load='4d10' size='340' side='right' caption=' | |||
'''COP9 (COnstitutive Photomorphogenesis 9) signalosome''' catalyzes the hydrolysis of NEDD8 protein from the cullin subunit of cullin-ring ubiquitin ligase. COP9 functions in the ubiquitin-proteasome pathway. COP9 contains 8 subunits and is homologous to the lid of the 26S proteasome. | '''COP9 (COnstitutive Photomorphogenesis 9) signalosome''' catalyzes the hydrolysis of NEDD8 protein from the cullin subunit of cullin-ring ubiquitin ligase. COP9 functions in the ubiquitin-proteasome pathway. COP9 contains 8 subunits and is homologous to the lid of the 26S proteasome. | ||
Revision as of 13:42, 8 July 2015
COP9 (COnstitutive Photomorphogenesis 9) signalosome catalyzes the hydrolysis of NEDD8 protein from the cullin subunit of cullin-ring ubiquitin ligase. COP9 functions in the ubiquitin-proteasome pathway. COP9 contains 8 subunits and is homologous to the lid of the 26S proteasome. FunctionDiseaseRelevanceStructural highlights |
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3D Structures of COP9 signalosome3D Structures of COP9 signalosome
Updated on 08-July-2015
4d0p – hCOP9 subunit 4 – human
1ufm – hCOP9 subunit 4 PCI domain - NMR
4f7o – hCOP9 subunit 5
4qft – hCOP9 subunit 6
4e0q, 4r14 – hCOP9 subunit 6 MPN domain
4d10, 4d18 – hCOP9 subunits 1,2,3,4,5,6,7A,8