3hvt: Difference between revisions

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[[Image:3hvt.gif|left|200px]]<br /><applet load="3hvt" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3hvt.gif|left|200px]]
caption="3hvt, resolution 2.9&Aring;" />
 
'''STRUCTURAL BASIS OF ASYMMETRY IN THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE HETERODIMER'''<br />
{{Structure
|PDB= 3hvt |SIZE=350|CAPTION= <scene name='initialview01'>3hvt</scene>, resolution 2.9&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NVP:11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE'>NVP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49]
|GENE=
}}
 
'''STRUCTURAL BASIS OF ASYMMETRY IN THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE HETERODIMER'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
3HVT is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=NVP:'>NVP</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. This structure supersedes the now removed PDB entries 2HVT and 1HVT. The following page contains interesting information on the relation of 3HVT with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb33_1.html Reverse Transcriptase]]. Active as [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HVT OCA].  
3HVT is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. This structure supersedes the now removed PDB entries 2HVT and 1HVT. The following page contains interesting information on the relation of 3HVT with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb33_1.html Reverse Transcriptase]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HVT OCA].  


==Reference==
==Reference==
Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer., Wang J, Smerdon SJ, Jager J, Kohlstaedt LA, Rice PA, Friedman JM, Steitz TA, Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7242-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7518928 7518928]
Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer., Wang J, Smerdon SJ, Jager J, Kohlstaedt LA, Rice PA, Friedman JM, Steitz TA, Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7242-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7518928 7518928]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: nucleotidyltransferase]]
[[Category: nucleotidyltransferase]]


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