4xfy: Difference between revisions

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-'''Unreleased structure'''
+==Structure of the native full-length dehydrated HIV-1 capsid protein==
+<StructureSection load='4xfy' size='340' side='right' caption='[[4xfy]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-The entry 4xfy is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4xfy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XFY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XFY FirstGlance]. <br>
-Authors: Gres, A.T., Kirby, K.A., Sarafianos, S.G.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xfx|4xfx]], [[4xfz|4xfz]]</td></tr>
-Description:
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xfy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xfy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xfy RCSB], [http://www.ebi.ac.uk/pdbsum/4xfy PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Sarafianos, S.G]]
+== Function ==
-[[Category: Kirby, K.A]]
+[[http://www.uniprot.org/uniprot/GAG_HV1N5 GAG_HV1N5]] Matrix protein p17 targets Gag and Gag-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex. Implicated in the release from host cell mediated by Vpu.  Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.  Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers.  p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1 (By similarity).
-[[Category: Gres, A.T]]
+__TOC__
+</StructureSection>
+[[Category: Gres, A T]]
+[[Category: Kirby, K A]]
+[[Category: Sarafianos, S G]]
+[[Category: Capsid protein]]
+[[Category: Dehydrated]]
+[[Category: Hiv-1]]
+[[Category: Native]]