3bhv: Difference between revisions

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-[[Image:3bhv.jpg|left|200px]]<br /><applet load="3bhv" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:3bhv.jpg|left|200px]]
-caption="3bhv, resolution 2.100&Aring;" />
-'''Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor variolin B'''<br />
+ {{Structure
+|PDB= 3bhv |SIZE=350|CAPTION= <scene name='initialview01'>3bhv</scene>, resolution 2.100&Aring;
+|SITE= <scene name='pdbsite=AC1:Mg+Binding+Site+For+Residue+B+1'>AC1</scene>, <scene name='pdbsite=AC2:Mg+Binding+Site+For+Residue+D+2'>AC2</scene>, <scene name='pdbsite=AC3:Var+Binding+Site+For+Residue+A+299'>AC3</scene>, <scene name='pdbsite=AC4:Var+Binding+Site+For+Residue+C+299'>AC4</scene>, <scene name='pdbsite=AC5:Sgm+Binding+Site+For+Residue+B+2'>AC5</scene>, <scene name='pdbsite=AC6:Sgm+Binding+Site+For+Residue+B+3'>AC6</scene> and <scene name='pdbsite=AC7:Sgm+Binding+Site+For+Residue+D+1'>AC7</scene>
+|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=VAR:'>VAR</scene> and <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22]
+|GENE= CDK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), CCNA2, CCNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus])
+}}
+'''Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor variolin B'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-BHV is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=VAR:'>VAR</scene> and <scene name='pdbligand=SGM:'>SGM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22] Known structural/functional Sites: <scene name='pdbsite=AC1:Mg+Binding+Site+For+Residue+B+1'>AC1</scene>, <scene name='pdbsite=AC2:Mg+Binding+Site+For+Residue+D+2'>AC2</scene>, <scene name='pdbsite=AC3:Var+Binding+Site+For+Residue+A+299'>AC3</scene>, <scene name='pdbsite=AC4:Var+Binding+Site+For+Residue+C+299'>AC4</scene>, <scene name='pdbsite=AC5:Sgm+Binding+Site+For+Residue+B+2'>AC5</scene>, <scene name='pdbsite=AC6:Sgm+Binding+Site+For+Residue+B+3'>AC6</scene> and <scene name='pdbsite=AC7:Sgm+Binding+Site+For+Residue+D+1'>AC7</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BHV OCA].
+BHV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BHV OCA].
 ==Reference==
-Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases., Bettayeb K, Tirado OM, Marionneau-Lambot S, Ferandin Y, Lozach O, Morris JC, Mateo-Lozano S, Drueckes P, Schachtele C, Kubbutat MH, Liger F, Marquet B, Joseph B, Echalier A, Endicott JA, Notario V, Meijer L, Cancer Res. 2007 Sep 1;67(17):8325-34. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17804748 17804748]
+Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases., Bettayeb K, Tirado OM, Marionneau-Lambot S, Ferandin Y, Lozach O, Morris JC, Mateo-Lozano S, Drueckes P, Schachtele C, Kubbutat MH, Liger F, Marquet B, Joseph B, Echalier A, Endicott JA, Notario V, Meijer L, Cancer Res. 2007 Sep 1;67(17):8325-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17804748 17804748]
 [[Category: Bos taurus]]
 [[Category: Cyclin-dependent kinase]]
@@ Line 43: / Line 52: @@
 [[Category: transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:05:42 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:59:00 2008''