3bef: Difference between revisions

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[[Image:3bef.jpg|left|200px]]<br /><applet load="3bef" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3bef.jpg|left|200px]]
caption="3bef, resolution 2.20&Aring;" />
 
'''Crystal structure of thrombin bound to the extracellular fragment of PAR1'''<br />
{{Structure
|PDB= 3bef |SIZE=350|CAPTION= <scene name='initialview01'>3bef</scene>, resolution 2.20&Aring;
|SITE= <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+E+302'>AC1</scene>
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE= F2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), F2R, CF2R, PAR1, TR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of thrombin bound to the extracellular fragment of PAR1'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
3BEF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Known structural/functional Site: <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+E+302'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BEF OCA].  
3BEF is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BEF OCA].  


==Reference==
==Reference==
Molecular dissection of Na+ binding to thrombin., Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E, J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15152000 15152000]
Molecular dissection of Na+ binding to thrombin., Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E, J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15152000 15152000]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: blood coagulation]]
[[Category: blood coagulation]]
[[Category: calcium]]
[[Category: calcium]]
[[Category: cleavage on pair of basic residues]]
[[Category: cleavage on pair of basic residue]]
[[Category: disease mutation]]
[[Category: disease mutation]]
[[Category: g-protein coupled receptor]]
[[Category: g-protein coupled receptor]]
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[[Category: zymogen]]
[[Category: zymogen]]


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