Adrenodoxin reductase: Difference between revisions

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Revision as of 19:47, 4 June 2015 view source Israel Hanukoglu (talk \| contribs) 113 edits Introduction ← Older edit		Revision as of 20:56, 4 June 2015 view source Israel Hanukoglu (talk \| contribs) 113 edits No edit summary Newer edit →
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	Adrenodoxin reductase (AR) is ~~the first enzyme~~ in the mitochondrial P450 systems that ~~are expressed~~ in ~~tissues that synthesize steroids~~.<ref name="HI-review">PMID:22217824</ref> AR is ~~an FAD containing flavoprotein that receives two electrons from NADPH and transfers them one at time to adrenodoxin that is an iron sulfur protein~~. ~~Reduced adrenodoxin in turn reduces mitochondrial P450s that catalyze essential steps in the biosynthesis of steroids, such as pregnenolone, cortisol, aldosterone and sex steroids~~.~~<ref name="HI-review"~~ />		Adrenodoxin reductase (AR) is an FAD containing flavoprotein that function as an electron transfer protein in the mitochondrial P450 systems that catalyze essential steps in biosynthesis of steroid hormones.<ref name="HI-review">PMID:22217824</ref>. Its enzyme nomenclature code is [http://www.chem.qmul.ac.uk/iubmb/enzyme/EC1/18/1/6.html 1.18.1.6].

	==References==		==References==