Beta2 adrenergic receptor-Gs protein complex: Difference between revisions
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== Complex structure == | == Complex structure == | ||
The overall structure shows the b2AR (dark blue) bound to an agonist (in spheres) along with a T4 lysozyme fused to its amino terminus in order to facilitate crystallization. The receptor interacts with Gas (light blue).Gas together with Gb (light green) and Gc (gold) constitute the heterotrimeric G protein Gs. A Gs-binding nanobody which also facilitates crystallization (pink) binds the G protein between the a and b subunits. | The overall structure shows the b2AR (dark blue) bound to an agonist (in spheres) along with a T4 lysozyme fused to its amino terminus in order to facilitate crystallization. The receptor interacts with Gas (light blue). Gas together with Gb (light green) and Gc (gold) constitute the heterotrimeric G protein Gs. A Gs-binding nanobody which also facilitates crystallization (pink) binds the G protein between the a and b subunits. | ||
== G-Protein-GPCR Intercations == | == G-Protein-GPCR Intercations == | ||