Beta2 adrenergic receptor-Gs protein complex: Difference between revisions

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== G-Protein variability ==
== G-Protein variability ==
The Gαs subunit consists of two domains, the Ras domain (αRas) and the α-helical domain (αAH). Both are involved in nucleotide binding. A big discovery made thanks to this structure is that the G alpha subunit has large variability between its GTP bound (active) and nucleotide free states, where <scene name='70/701430/Gamorph/1'>the αAH domain has a variable position relative to the αRas domain</scene>
The Gαs subunit consists of two domains, the Ras domain (αRas) and the α-helical domain (αAH). Both are involved in nucleotide binding. A big discovery made thanks to this structure is that the G alpha subunit has large variability between its GTP bound (active) and nucleotide free states, where <scene name='70/701430/Gamorph/2'>the αAH domain has a variable position relative to the αRas domain</scene>


==See Also==
==See Also==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Dan Elran, Michal Harel, Joel L. Sussman, Alexander Berchansky