Beta2 adrenergic receptor-Gs protein complex: Difference between revisions
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== G-Protein-GPCR Intercations == | == G-Protein-GPCR Intercations == | ||
The a5-helix of Gas docks into a cavity formed on the intracellular side of the receptor by the opening of transmembrane helices 5 and 6. Within the transmembrane core, the interactions are primarily non-polar. An exception involves <scene name='70/701430/Receptor_g_protein_interaction/ | The a5-helix of Gas docks into a cavity formed on the intracellular side of the receptor by the opening of transmembrane helices 5 and 6. Within the transmembrane core, the interactions are primarily non-polar. An exception involves <scene name='70/701430/Receptor_g_protein_interaction/4'>packing of Tyr 391 of the a5-helix against Arg 131 of the conservedDRYsequence inTM3. Arg 131 also packs against Tyr 326 of the conserved | ||
NPxxY sequence in TM7</scene> | NPxxY sequence in TM7</scene> | ||