2f8a: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
Line 2: Line 2:
<StructureSection load='2f8a' size='340' side='right' caption='[[2f8a]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='2f8a' size='340' side='right' caption='[[2f8a]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2f8a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F8A FirstGlance]. <br>
<table><tr><td colspan='2'>[[2f8a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F8A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GPX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GPX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_peroxidase Glutathione peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.9 1.11.1.9] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_peroxidase Glutathione peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.9 1.11.1.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f8a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f8a RCSB], [http://www.ebi.ac.uk/pdbsum/2f8a PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f8a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f8a RCSB], [http://www.ebi.ac.uk/pdbsum/2f8a PDBsum]</span></td></tr>
Line 26: Line 26:
</StructureSection>
</StructureSection>
[[Category: Glutathione peroxidase]]
[[Category: Glutathione peroxidase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Delft, F von]]
[[Category: Delft, F von]]
[[Category: Edwards, A]]
[[Category: Edwards, A]]

Revision as of 08:48, 30 April 2015

Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1

Structural highlights

2f8a is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:GPX1 (HUMAN)
Activity:Glutathione peroxidase, with EC number 1.11.1.9
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[GPX1_HUMAN] Protects the hemoglobin in erythrocytes from oxidative breakdown.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2f8a, resolution 1.50Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA