DeepView/Mutating Amino Acids: Difference between revisions
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Caution: DeepView cannot predict changes in overall protein conformation after mutating amino acids, and it is unlikely that any existing program can do this. Therefore, mutating one or more amino acids in an existing protein model will allow you to visualize the mutated sidechains in the context of the wild-type protein structure, but the resultating mutated model may not reflect changes that such mutations may induce in protein structure. | Caution: DeepView cannot predict changes in overall protein conformation after mutating amino acids, and it is unlikely that any existing program can do this reliably. Therefore, mutating one or more amino acids in an existing protein model will allow you to visualize the mutated sidechains in the context of the wild-type protein structure, but the resultating mutated model may not reflect changes that such mutations may induce in protein structure. | ||
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Revision as of 20:48, 29 April 2015
DeepView is a free molecular modeling program available for both Windows and OS X. Here are instructions for using DeepView to mutate an amino acid.
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Caution: DeepView cannot predict changes in overall protein conformation after mutating amino acids, and it is unlikely that any existing program can do this reliably. Therefore, mutating one or more amino acids in an existing protein model will allow you to visualize the mutated sidechains in the context of the wild-type protein structure, but the resultating mutated model may not reflect changes that such mutations may induce in protein structure. |