2v2c: Difference between revisions

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OCA

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-[[Image:2v2c.jpg|left|200px]]<br /><applet load="2v2c" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2v2c.jpg|left|200px]]
-caption="2v2c, resolution 1.89&Aring;" />
-'''THE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIM'''<br />
+ {{Structure
+|PDB= 2v2c |SIZE=350|CAPTION= <scene name='initialview01'>2v2c</scene>, resolution 1.89&Aring;
+|SITE= <scene name='pdbsite=AC1:Binding+Site+For+Residue+So4+A+1251'>AC1</scene>, <scene name='pdbsite=AC2:Binding+Site+For+Residue+So4+A+1252'>AC2</scene>, <scene name='pdbsite=AC3:Binding+Site+For+Residue+So4+A+1253'>AC3</scene> and <scene name='pdbsite=AC4:Binding+Site+For+Residue+Pga+A+1254'>AC4</scene>
+|LIGAND= <scene name='pdbligand=PGA:2-PHOSPHOGLYCOLIC+ACID'>PGA</scene> and <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1]
+|GENE=
+}}
+'''THE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIM'''
 ==Overview==
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 ==About this Structure==
-V2C is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei] with <scene name='pdbligand=PGA:'>PGA</scene> and <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] Known structural/functional Sites: <scene name='pdbsite=AC1:Binding+Site+For+Residue+So4+A+1251'>AC1</scene>, <scene name='pdbsite=AC2:Binding+Site+For+Residue+So4+A+1252'>AC2</scene>, <scene name='pdbsite=AC3:Binding+Site+For+Residue+So4+A+1253'>AC3</scene> and <scene name='pdbsite=AC4:Binding+Site+For+Residue+Pga+A+1254'>AC4</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V2C OCA].
+V2C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V2C OCA].
 ==Reference==
-Structural studies show that the A178L mutation in the C-terminal hinge of the catalytic loop-6 of triosephosphate isomerase (TIM) induces a closed-like conformation in dimeric and monomeric TIM., Alahuhta M, Casteleijn MG, Neubauer P, Wierenga RK, Acta Crystallogr D Biol Crystallogr. 2008 Feb;64(Pt 2):178-88. Epub 2008, Jan 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18219118 18219118]
+Structural studies show that the A178L mutation in the C-terminal hinge of the catalytic loop-6 of triosephosphate isomerase (TIM) induces a closed-like conformation in dimeric and monomeric TIM., Alahuhta M, Casteleijn MG, Neubauer P, Wierenga RK, Acta Crystallogr D Biol Crystallogr. 2008 Feb;64(Pt 2):178-88. Epub 2008, Jan 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18219118 18219118]
 [[Category: Single protein]]
 [[Category: Triose-phosphate isomerase]]
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 [[Category: triosephosphate isomerase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:52:51 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:42:39 2008''