2v0z: Difference between revisions

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OCA

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-[[Image:2v0z.jpg|left|200px]]<br /><applet load="2v0z" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2v0z.jpg|left|200px]]
-caption="2v0z, resolution 2.2&Aring;" />
-'''CRYSTAL STRUCTURE OF RENIN WITH INHIBITOR 10 (ALISKIREN)'''<br />
+ {{Structure
+|PDB= 2v0z |SIZE=350|CAPTION= <scene name='initialview01'>2v0z</scene>, resolution 2.2&Aring;
+|SITE= <scene name='pdbsite=AC1:Ndg+Binding+Site+For+Chain+O'>AC1</scene>
+|LIGAND= <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene> and <scene name='pdbligand=C41:ALISKIREN'>C41</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15]
+|GENE=
+}}
+'''CRYSTAL STRUCTURE OF RENIN WITH INHIBITOR 10 (ALISKIREN)'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-V0Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NDG:'>NDG</scene> and <scene name='pdbligand=C41:'>C41</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15] Known structural/functional Site: <scene name='pdbsite=AC1:Ndg+Binding+Site+For+Chain+O'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V0Z OCA].
+V0Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V0Z OCA].
 ==Reference==
-Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin., Rahuel J, Rasetti V, Maibaum J, Rueger H, Goschke R, Cohen NC, Stutz S, Cumin F, Fuhrer W, Wood JM, Grutter MG, Chem Biol. 2000 Jul;7(7):493-504. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10903938 10903938]
+Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin., Rahuel J, Rasetti V, Maibaum J, Rueger H, Goschke R, Cohen NC, Stutz S, Cumin F, Fuhrer W, Wood JM, Grutter MG, Chem Biol. 2000 Jul;7(7):493-504. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10903938 10903938]
 [[Category: Homo sapiens]]
 [[Category: Renin]]
@@ Line 32: / Line 41: @@
 [[Category: alternative splicing]]
 [[Category: aspartyl protease]]
-[[Category: cleavage on pair of basic residues]]
+[[Category: cleavage on pair of basic residue]]
 [[Category: glycoprotein]]
 [[Category: hydrolase]]
@@ Line 41: / Line 50: @@
 [[Category: zymogen]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:52:24 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:42:08 2008''