Flavodoxin

Flavodoxin (FDX) is a bacterial protein which contains flavin mononucleotide (FMN) or flavin adenine dinucleotide (FAD). It participates in nitrogen metabolism and reduces N2 to NH3 while changing from its oxidized quinone state FDX-ox via semiquinone FDX-sq to its reduced hydroquinone state FDX-red. NrdI is a FDX which is involved in ribonucleotide reduction. WrbA (Tryptophan Repressor-Binding Protein) is also FDX. In E. coli there are 2 distinct FDX I and II. The space filling objects are of chloride ion and benzamidine.

3D Structures of Flavodoxin3D Structures of Flavodoxin

Updated on 05-April-2015

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• Apo FDX
  • 2kqu, 1dx9 – AnFDX (mutant) apo – Anabanea – NMR
    
  • 2bmv – HpFDX apo - Helicobacter pylori
    
  • 3d7n – FDX apo – Agrobacterium tumefaciens
    
  • 2rg1 - EcFDX WrbA apo - Escherichia coli
    
  • 2hna, 2hnb, 2m6r, 2m6s – EcFDX apo – NMR
    
  • 1qhe, 1ftg – nFDX apo – Nostoc
    
  • 1bu5 – DvFDX apo+riboflavin - Desulfovibrio vulgaris
    
• FDX containing FMN oxidized (quinone)
  • 3f6r, 3f6s, 3kap – DdFDX-ox - Desulfovibrio desulfuricans
    
  • 4heq - FDX-ox – Desulfovibrio gigas
    
  • 1ag9 – EcFDX-ox
    
  • 1flv – nFDX-ox
    
  • 1xyy, 1j9g, 1c7f, 1akr, 1akt, 1akw – DvFDX-ox (mutant)
    
  • 2fx2, 3fx2, 4fx2, 5fx2, 1fx1 – DvFDX-ox
    
  • 1czk, 1czr – SeFDX-ox (mutant) - Synechococcus elongates
    
  • 1czn – SeFDX-ox I
    
  • 1ofv – SeFDX-ox II
    
  • 1czu, 1d03 - SeFDX-ox II
    
  • 2fdx, 1fld, 1fvx, 2fax, 3nll, 4nll, 4nul, 5nll – CbFDX-ox (mutant) - Clostridium beijerinckii
    
  • 2fcr – FDX-ox – Chondrus crispus
    
  • 1fue – HpFDX-ox
    
  • 4j8p - FDX-ox – Bacterioides uniformis
    
  • 1i1o - DvFDX-ox
    
• FDX containing FMNH (semiquinone)
  • 2x2o, 2x2p – NrdI-sq – Bacillus cereus
    
  • 3kaq, 3f90 – DdFDX-sq
    
  • 1xt6, 1wsw, 1xyv, 1akv, 1wsb - DvFDX-sq (mutant)
    
  • 1czh, 1czl - SeFDX-sq (mutant)
    
  • 2fox, 5nul– CbFDX-sq
    
• FDX containing FMNH2 (hydroquinone)
  • 2fz5 – FDX-red – Megasphaera elsdenii – NMR
    
  • 1c7e, 1aku, 1akq - DvFDX-red (mutant)
    
  • 1czo - SeFDX-red (mutant)
    
  • 1d04 – SeFDX-red
    
  • 1fla, 1fln, 2flv, 2fvx, 5ull, 6nul – CbFDX-red (mutant)
    
• Other FDX
  • 3esx, 3esy, 3esz, 2v5u, 2v5v, 1obo, 1obv - AnFDX (mutant)
    
  • 1rcf, 1flv - AnFDX
    
  • 2wc1 – FDX – Rhodobacter capsulatus
    
  • 2w5u – HpFDX+C3 inhibitor 1fue - HpFDX
    
  • 2kaq – DdFDX
    
  • 2r97, 2r96 – EcFDX WrbA
    
  • 1ahn – EcFDX
    
  • 2q9u – FDX di-iron – Giardia intestinalis
    
  • 2ark – FDX – Aquifex aeolicus
    
  • 1yob – FDX II – Azotobacter vinelandii
    
  • 1j9e, 1f4p, 1i10, 1azl – DvFDX (mutant)
    
  • 1j8q - DvFDX