2rk8: Difference between revisions
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[[Image:2rk8.jpg|left|200px]] | [[Image:2rk8.jpg|left|200px]] | ||
'''The Structure of rat cytosolic PEPCK in complex with phosphonoformate''' | {{Structure | ||
|PDB= 2rk8 |SIZE=350|CAPTION= <scene name='initialview01'>2rk8</scene>, resolution 2.000Å | |||
|SITE= <scene name='pdbsite=AC1:Mn+Binding+Site+For+Residue+A+700'>AC1</scene>, <scene name='pdbsite=AC2:Na+Binding+Site+For+Residue+A+624'>AC2</scene>, <scene name='pdbsite=AC3:Mn+Binding+Site+For+Residue+B+700'>AC3</scene>, <scene name='pdbsite=AC4:Na+Binding+Site+For+Residue+B+624'>AC4</scene>, <scene name='pdbsite=AC5:Ppf+Binding+Site+For+Residue+A+3969'>AC5</scene>, <scene name='pdbsite=AC6:Ppf+Binding+Site+For+Residue+B+3969'>AC6</scene>, <scene name='pdbsite=AC7:Fmt+Binding+Site+For+Residue+A+3406'>AC7</scene>, <scene name='pdbsite=AC8:Peg+Binding+Site+For+Residue+A+5759'>AC8</scene> and <scene name='pdbsite=AC9:Fmt+Binding+Site+For+Residue+B+3406'>AC9</scene> | |||
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PPF:PHOSPHONOFORMIC+ACID'>PPF</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene> and <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(GTP) Phosphoenolpyruvate carboxykinase (GTP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.32 4.1.1.32] | |||
|GENE= Pck1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus]) | |||
}} | |||
'''The Structure of rat cytosolic PEPCK in complex with phosphonoformate''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2RK8 is a [ | 2RK8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RK8 OCA]. | ||
==Reference== | ==Reference== | ||
Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition., Stiffin RM, Sullivan SM, Carlson GM, Holyoak T, Biochemistry. 2008 Feb 19;47(7):2099-109. Epub 2008 Jan 16. PMID:[http:// | Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition., Stiffin RM, Sullivan SM, Carlson GM, Holyoak T, Biochemistry. 2008 Feb 19;47(7):2099-109. Epub 2008 Jan 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18197707 18197707] | ||
[[Category: Phosphoenolpyruvate carboxykinase (GTP)]] | [[Category: Phosphoenolpyruvate carboxykinase (GTP)]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
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[[Category: nucleotide-binding]] | [[Category: nucleotide-binding]] | ||
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