2rdu: Difference between revisions
New page: left|200px<br /><applet load="2rdu" size="350" color="white" frame="true" align="right" spinBox="true" caption="2rdu, resolution 1.650Å" /> '''Crystal Structure o... |
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[[Image:2rdu.jpg|left|200px]] | [[Image:2rdu.jpg|left|200px]] | ||
'''Crystal Structure of Human Glycolate Oxidase in Complex with Glyoxylate''' | {{Structure | ||
|PDB= 2rdu |SIZE=350|CAPTION= <scene name='initialview01'>2rdu</scene>, resolution 1.650Å | |||
|SITE= <scene name='pdbsite=AC1:Fmn+Binding+Site+For+Residue+A+371'>AC1</scene> and <scene name='pdbsite=AC2:Glv+Binding+Site+For+Residue+A+372'>AC2</scene> | |||
|LIGAND= <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene> and <scene name='pdbligand=GLV:GLYOXYLIC ACID'>GLV</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/(S)-2-hydroxy-acid_oxidase (S)-2-hydroxy-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15] | |||
|GENE= HAO1, GOX1, HAOX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Crystal Structure of Human Glycolate Oxidase in Complex with Glyoxylate''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2RDU is a [ | 2RDU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RDU OCA]. | ||
==Reference== | ==Reference== | ||
Active Site and Loop 4 Movements within Human Glycolate Oxidase: Implications for Substrate Specificity and Drug Design., Murray MS, Holmes RP, Lowther WT, Biochemistry. 2008 Feb 26;47(8):2439-49. Epub 2008 Jan 24. PMID:[http:// | Active Site and Loop 4 Movements within Human Glycolate Oxidase: Implications for Substrate Specificity and Drug Design., Murray MS, Holmes RP, Lowther WT, Biochemistry. 2008 Feb 26;47(8):2439-49. Epub 2008 Jan 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18215067 18215067] | ||
[[Category: (S)-2-hydroxy-acid oxidase]] | [[Category: (S)-2-hydroxy-acid oxidase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: peroxisome]] | [[Category: peroxisome]] | ||
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