Molecular Playground/OmpG: Difference between revisions
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==Outer Membrane Protein G== | ==Outer Membrane Protein G== | ||
<Structure load='2iww' size='500' frame='true' align='right' caption='Outer Membrane Protein G complex with glucose, octylglucoside and lauryl dimethylamine oxide (PDB code [[2iww]]).' scene=''> | <Structure load='2iww' size='500' frame='true' align='right' caption='Outer Membrane Protein G complex with glucose, octylglucoside and lauryl dimethylamine oxide (PDB code [[2iww]]).' scene='User:Christina_Chisholm/Sandbox_1/Greenwoselection_ompg/5'/> | ||
Protein biosensors serve as an analytical device combining a biological component with a physiochemical detector. Through protein engineering we are able to utilize pores as stochastic sensors for single molecule detection. The applications of biosensors range from fundamental research, clinical diagnosis and even advances in homeland security. PCR (Polymerase chain reaction) and ELISA (Enzyme- linked immunosorbent assay) are current sensitive detection methods. However, these methods are time consuming and require laborious effort, where results are provided hours or days later. For this reason alternate approaches are mounting in demands that are rapid in detection time, highly sensitive and reliable. | Protein biosensors serve as an analytical device combining a biological component with a physiochemical detector. Through protein engineering we are able to utilize pores as stochastic sensors for single molecule detection. The applications of biosensors range from fundamental research, clinical diagnosis and even advances in homeland security. PCR (Polymerase chain reaction) and ELISA (Enzyme- linked immunosorbent assay) are current sensitive detection methods. However, these methods are time consuming and require laborious effort, where results are provided hours or days later. For this reason alternate approaches are mounting in demands that are rapid in detection time, highly sensitive and reliable. | ||