2qmd: Difference between revisions

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-[[Image:2qmd.jpg|left|200px]]<br /><applet load="2qmd" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2qmd.jpg|left|200px]]
-caption="2qmd, resolution 1.650&Aring;" />
-'''Structure of BACE Bound to SCH722924'''<br />
+ {{Structure
+|PDB= 2qmd |SIZE=350|CAPTION= <scene name='initialview01'>2qmd</scene>, resolution 1.650&Aring;
+|SITE= <scene name='pdbsite=AC1:Cs7+Binding+Site+For+Residue+A+1'>AC1</scene>, <scene name='pdbsite=AC2:Cs7+Binding+Site+For+Residue+B+1'>AC2</scene>, <scene name='pdbsite=AC3:Tar+Binding+Site+For+Residue+A+448'>AC3</scene>, <scene name='pdbsite=AC4:Tar+Binding+Site+For+Residue+A+2'>AC4</scene> and <scene name='pdbsite=AC5:Tar+Binding+Site+For+Residue+B+3'>AC5</scene>
+|LIGAND= <scene name='pdbligand=CS7:'>CS7</scene> and <scene name='pdbligand=TAR:D(-)-TARTARIC ACID'>TAR</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46]
+|GENE= BACE1, BACE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''Structure of BACE Bound to SCH722924'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-QMD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CS7:'>CS7</scene> and <scene name='pdbligand=TAR:'>TAR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] Known structural/functional Sites: <scene name='pdbsite=AC1:Cs7+Binding+Site+For+Residue+A+1'>AC1</scene>, <scene name='pdbsite=AC2:Cs7+Binding+Site+For+Residue+B+1'>AC2</scene>, <scene name='pdbsite=AC3:Tar+Binding+Site+For+Residue+A+448'>AC3</scene>, <scene name='pdbsite=AC4:Tar+Binding+Site+For+Residue+A+2'>AC4</scene> and <scene name='pdbsite=AC5:Tar+Binding+Site+For+Residue+B+3'>AC5</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QMD OCA].
+QMD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QMD OCA].
 ==Reference==
-Potent pyrrolidine- and piperidine-based BACE-1 inhibitors., Iserloh U, Wu Y, Cumming JN, Pan J, Wang LY, Stamford AW, Kennedy ME, Kuvelkar R, Chen X, Parker EM, Strickland C, Voigt J, Bioorg Med Chem Lett. 2008 Jan 1;18(1):414-7. Epub 2007 Nov 6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18023580 18023580]
+Potent pyrrolidine- and piperidine-based BACE-1 inhibitors., Iserloh U, Wu Y, Cumming JN, Pan J, Wang LY, Stamford AW, Kennedy ME, Kuvelkar R, Chen X, Parker EM, Strickland C, Voigt J, Bioorg Med Chem Lett. 2008 Jan 1;18(1):414-7. Epub 2007 Nov 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18023580 18023580]
 [[Category: Homo sapiens]]
 [[Category: Memapsin 2]]
@@ Line 28: / Line 37: @@
 [[Category: zymogen]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Mar 14 09:34:54 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:27:19 2008''