JMS/Sandbox28: Difference between revisions
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=== Function=== | === Function=== | ||
Dronpa works by switching between the cis (bright state) to trans (dark state) position of a few amino acids in the chromophore center of the Beta-barrel structure. The amino acids that are key for this change are CYG Tripeptide in the chromophore Cys 62, Tyr 63, and Gly 64. There are also changes in conformation of four additional amino acids that are near the chromophore, Arg 66, Ser 142, Val 157, and His 193<ref> Biochem J. (2007) 402, 35-42 </ref>. | Dronpa works by switching between the cis (bright state) to trans (dark state) position of a few amino acids in the chromophore center of the Beta-barrel structure. The amino acids that are key for this change are CYG Tripeptide in the chromophore Cys 62, Tyr 63, and Gly 64. There are also changes in conformation of four additional amino acids that are near the chromophore, Arg 66, Ser 142, Val 157, and His 193, all <scene name='69/696906/Dronpa_switch/1'>labelled here</scene><ref> Biochem J. (2007) 402, 35-42 </ref>. | ||
==3D structures of Dronpa== | ==3D structures of Dronpa== | ||