2qk8: Difference between revisions
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[[Image:2qk8.jpg|left|200px]] | [[Image:2qk8.jpg|left|200px]] | ||
'''Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase''' | {{Structure | ||
|PDB= 2qk8 |SIZE=350|CAPTION= <scene name='initialview01'>2qk8</scene>, resolution 2.40Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] | |||
|GENE= dfrA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis]) | |||
}} | |||
'''Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2QK8 is a [ | 2QK8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QK8 OCA]. | ||
==Reference== | ==Reference== | ||
Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase., Bennett BC, Xu H, Simmerman RF, Lee RE, Dealwis CG, J Med Chem. 2007 Sep 6;50(18):4374-81. Epub 2007 Aug 14. PMID:[http:// | Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase., Bennett BC, Xu H, Simmerman RF, Lee RE, Dealwis CG, J Med Chem. 2007 Sep 6;50(18):4374-81. Epub 2007 Aug 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17696333 17696333] | ||
[[Category: Bacillus anthracis]] | [[Category: Bacillus anthracis]] | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
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[[Category: pteridine binding]] | [[Category: pteridine binding]] | ||
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