Recombinase A: Difference between revisions
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<Structure load='2REB' size='400' color='black' frame='true' align='right'/> | <Structure load='2REB' size='400' color='black' frame='true' align='right'/> | ||
<scene name='41/413118/Reca_active_filament/1'>RecA active filament</scene> | <scene name='41/413118/Reca_active_filament/1'>RecA active filament</scene> | ||
<scene name='41/413118/Reca_adp_mg/ | <scene name='41/413118/Reca_adp_mg/2'>RecA with ADP and Mg bound</scene> | ||
[[Recombinase A]] (RecA) is a naturally aggregating 352 amino acid proteinT1 involved in DNA repair, is an important asset to the genetic integrity of the ''Escherichia coli'' (''E. coli'') genome. The survival of all species rely on such DNA repair processes. RecA homologues are found in all kingdoms including archaebacteria, eubacteria, and eukaryotes.T3 RAD51, for example, is a RecA homologue found specifically in humans.T4 An over-expression of RAD51 in the nuclei of tumor cells when compared to those of normal breast tissue has been linked to sporadic, non-hereditary, breast cancers.T5 | [[Recombinase A]] (RecA) is a naturally aggregating 352 amino acid proteinT1 involved in DNA repair, is an important asset to the genetic integrity of the ''Escherichia coli'' (''E. coli'') genome. The survival of all species rely on such DNA repair processes. RecA homologues are found in all kingdoms including archaebacteria, eubacteria, and eukaryotes.T3 RAD51, for example, is a RecA homologue found specifically in humans.T4 An over-expression of RAD51 in the nuclei of tumor cells when compared to those of normal breast tissue has been linked to sporadic, non-hereditary, breast cancers.T5 | ||