2pha: Difference between revisions

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[[Image:2pha.jpg|left|200px]]<br /><applet load="2pha" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2pha.jpg|left|200px]]
caption="2pha, resolution 1.90&Aring;" />
 
'''Crystal structure of native, unliganded human arginase at 1.90 resolution'''<br />
{{Structure
|PDB= 2pha |SIZE=350|CAPTION= <scene name='initialview01'>2pha</scene>, resolution 1.90&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MN:MANGANESE (II) ION'>MN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1]
|GENE= ARG1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of native, unliganded human arginase at 1.90 resolution'''
 


==About this Structure==
==About this Structure==
2PHA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MN:'>MN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHA OCA].  
2PHA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHA OCA].  


==Reference==
==Reference==
Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster., Di Costanzo L, Pique ME, Christianson DW, J Am Chem Soc. 2007 May 23;129(20):6388-9. Epub 2007 May 1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17469833 17469833]
Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster., Di Costanzo L, Pique ME, Christianson DW, J Am Chem Soc. 2007 May 23;129(20):6388-9. Epub 2007 May 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17469833 17469833]
[[Category: Arginase]]
[[Category: Arginase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: proton wire]]
[[Category: proton wire]]


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