2pgz: Difference between revisions

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[[Image:2pgz.jpg|left|200px]]<br /><applet load="2pgz" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2pgz.jpg|left|200px]]
caption="2pgz, resolution 1.76&Aring;" />
 
'''Crystal structure of Cocaine bound to an ACh-Binding Protein'''<br />
{{Structure
|PDB= 2pgz |SIZE=350|CAPTION= <scene name='initialview01'>2pgz</scene>, resolution 1.76&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=COC:COCAINE'>COC</scene> and <scene name='pdbligand=PG4:TETRAETHYLENE GLYCOL'>PG4</scene>
|ACTIVITY=
|GENE= synthetic ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6500 Aplysia californica])
}}
 
'''Crystal structure of Cocaine bound to an ACh-Binding Protein'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2PGZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=COC:'>COC</scene> and <scene name='pdbligand=PG4:'>PG4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PGZ OCA].  
2PGZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PGZ OCA].  


==Reference==
==Reference==
Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors., Hansen SB, Taylor P, J Mol Biol. 2007 Jun 15;369(4):895-901. Epub 2007 Mar 31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17481657 17481657]
Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors., Hansen SB, Taylor P, J Mol Biol. 2007 Jun 15;369(4):895-901. Epub 2007 Mar 31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17481657 17481657]
[[Category: Aplysia californica]]
[[Category: Aplysia californica]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: cocaine]]
[[Category: cocaine]]
[[Category: galanthamine]]
[[Category: galanthamine]]
[[Category: nicotinic acetycholine receptors]]
[[Category: nicotinic acetycholine receptor]]
[[Category: non-competitive inhibitors]]
[[Category: non-competitive inhibitor]]


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