2ph0: Difference between revisions

← Older edit Newer edit →

Revision as of 19:12, 20 March 2008

File:2ph0.gif

, resolution 1.85Å

Gene:

ECA3008 (Pectobacterium carotovorum)

Coordinates:

save as pdb, mmCIF, xml

Crystal structure of the Q6D2T7_ERWCT protein from Erwinia carotovora. NESG target EwR41.

OverviewOverview

We report here the crystal structure at 2.0 A resolution of the AGR_C_4470p protein from the Gram-negative bacterium Agrobacterium tumefaciens. The protein is a tightly associated dimer, each subunit of which bears strong structural homology with the two domains of the heme utilization protein ChuS from Escherichia coli and HemS from Yersinia enterocolitica. Remarkably, the organization of the AGR_C_4470p dimer is the same as that of the two domains in ChuS and HemS, providing structural evidence that these two proteins evolved by gene duplication. However, the binding site for heme, while conserved in HemS and ChuS, is not conserved in AGR_C_4470p, suggesting that it probably has a different function. This is supported by the presence of two homologs of AGR_C_4470p in E. coli, in addition to the ChuS protein.

About this StructureAbout this Structure

2PH0 is a Single protein structure of sequence from Pectobacterium carotovorum. Full crystallographic information is available from OCA.

ReferenceReference

Crystal structure of AGR_C_4470p from Agrobacterium tumefaciens., Vorobiev SM, Neely H, Seetharaman J, Ma LC, Xiao R, Acton TB, Montelione GT, Tong L, Protein Sci. 2007 Mar;16(3):535-8. PMID:17322535

Page seeded by OCA on Thu Mar 20 18:12:52 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:2ph0.gif|left|200px]]<br /><applet load="2ph0" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2ph0.gif|left|200px]]
-caption="2ph0, resolution 1.85&Aring;" />
-'''Crystal structure of the Q6D2T7_ERWCT protein from Erwinia carotovora. NESG target EwR41.'''<br />
+ {{Structure
+|PDB= 2ph0 |SIZE=350|CAPTION= <scene name='initialview01'>2ph0</scene>, resolution 1.85&Aring;
+|SITE=
+|LIGAND=
+|ACTIVITY=
+|GENE= ECA3008 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=554 Pectobacterium carotovorum])
+}}
+'''Crystal structure of the Q6D2T7_ERWCT protein from Erwinia carotovora. NESG target EwR41.'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-PH0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pectobacterium_carotovorum Pectobacterium carotovorum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PH0 OCA].
+PH0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pectobacterium_carotovorum Pectobacterium carotovorum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PH0 OCA].
 ==Reference==
-Crystal structure of AGR_C_4470p from Agrobacterium tumefaciens., Vorobiev SM, Neely H, Seetharaman J, Ma LC, Xiao R, Acton TB, Montelione GT, Tong L, Protein Sci. 2007 Mar;16(3):535-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17322535 17322535]
+Crystal structure of AGR_C_4470p from Agrobacterium tumefaciens., Vorobiev SM, Neely H, Seetharaman J, Ma LC, Xiao R, Acton TB, Montelione GT, Tong L, Protein Sci. 2007 Mar;16(3):535-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17322535 17322535]
 [[Category: Pectobacterium carotovorum]]
 [[Category: Single protein]]
@@ Line 34: / Line 43: @@
 [[Category: psi-2]]
 [[Category: q6d2t7]]
-[[Category: structural genomics]]
+[[Category: structural genomic]]
 [[Category: unknown function]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:29:20 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:12:52 2008''