Mycobacterium tuberculosis ArfA Rv0899: Difference between revisions
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2. Rapid ammonia secretion to external environment: | 2. Rapid ammonia secretion to external environment: | ||
deamidation of the amino acid pair <scene name='61/612805/Asn111_and_gly112/1'> Asn111-Gly112 </scene>, located at the end of α1 and preceding L3, a pH-dependent reaction whereby Asn is converted to Asp and ammonia is released. Asparagine residues preceding glycine, and situated in conformationally flexible regions of proteins, are frequently deamidated, with potentially significant consequences for protein regulation and function <ref>PMID: 20199110</ref>. [[Image:Asparaginase-reaction.jpg|250px]] | deamidation of the amino acid pair <scene name='61/612805/Asn111_and_gly112/1'> Asn111-Gly112 </scene>, located at the end of α1 and preceding L3, a pH-dependent reaction whereby Asn is converted to Asp and ammonia is released. Asparagine residues preceding glycine, and situated in conformationally flexible regions of proteins, are frequently deamidated, with potentially significant consequences for protein regulation and function <ref>PMID: 20199110</ref>. [[Image:Asparaginase-reaction.jpg|250px]] | ||
3. Stabilization of the outer membrane: | 3. Stabilization of the outer membrane: | ||