2p4y: Difference between revisions

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[[Image:2p4y.jpg|left|200px]]<br /><applet load="2p4y" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2p4y.jpg|left|200px]]
caption="2p4y, resolution 2.25&Aring;" />
 
'''Crystal structure of human PPAR-gamma-ligand binding domain complexed with an indole-based modulator'''<br />
{{Structure
|PDB= 2p4y |SIZE=350|CAPTION= <scene name='initialview01'>2p4y</scene>, resolution 2.25&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=C03:'>C03</scene> and <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>
|ACTIVITY=
|GENE= PPARG, NR1C3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of human PPAR-gamma-ligand binding domain complexed with an indole-based modulator'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2P4Y is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=C03:'>C03</scene> and <scene name='pdbligand=TRS:'>TRS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P4Y OCA].  
2P4Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P4Y OCA].  


==Reference==
==Reference==
The differential interactions of peroxisome proliferator-activated receptor gamma ligands with Tyr473 is a physical basis for their unique biological activities., Einstein M, Akiyama TE, Castriota GA, Wang CF, McKeever B, Mosley RT, Becker JW, Moller DE, Meinke PT, Wood HB, Berger JP, Mol Pharmacol. 2008 Jan;73(1):62-74. Epub 2007 Oct 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17940191 17940191]
The differential interactions of peroxisome proliferator-activated receptor gamma ligands with Tyr473 is a physical basis for their unique biological activities., Einstein M, Akiyama TE, Castriota GA, Wang CF, McKeever B, Mosley RT, Becker JW, Moller DE, Meinke PT, Wood HB, Berger JP, Mol Pharmacol. 2008 Jan;73(1):62-74. Epub 2007 Oct 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17940191 17940191]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transcription]]
[[Category: transcription]]


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